INSTITUT FÜR MEDIZINISCHE INFORMATIK, STATISTIK UND EPIDEMIOLOGIE

Publikationen in Zeitschriften seit 1994

Insgesamt wurden 310 Artikel in begutachteten Zeitschriften veröffentlicht.

  • Bjoern Chapuy, Chip Stewart, Andrew J. Dunford, Jaegil Kim, Atanas Kamburov, Robert A. Redd, Mike S. Lawrence, Margaretha G. M. Roemer, Amy J. Li, Marita Ziepert, Annette M. Staiger, Jeremiah A. Wala, Matthew D. Ducar, Ignaty Leshchiner, Ester Rheinbay, Amaro Taylor-Weiner, Caroline A. Coughlin, Julian M. Hess, Chandra S. Pedamallu, Dimitri Livitz, Daniel Rosebrock, Mara Rosenberg, Adam A. Tracy, Heike Horn, Paul van Hummelen, Andrew L. Feldman, Brian K. Link, Anne J. Novak, James R. Cerhan, Thomas M. Habermann, Reiner Siebert, Andreas Rosenwald, Aaron R. Thorner, Matthew L. Meyerson, Todd R. Golub, Rameen Beroukhim, Gerald G. Wulf, German Ott, Scott J. Rodig, Stefano Monti, Donna S. Neuberg, Markus Loeffler, Michael Pfreundschuh, Lorenz Trümper, Gad Getz, Margaret A. Shipp
    (2018)
    Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes
    Nature medicine, 24(5), 679-690
    (Impactfactor: 29,886)
    PDF Download (3,8 MB, Englisch, 19 Seiten) BibTeX-Ausgabe
  • Julia Dittrich, Melanie Adam, Hilke Maas, Max Hecht, Madlen Reinicke, L. Renee Ruhaak, Christa Cobbaert, Christoph Engel, Kerstin Wirkner, Markus Löffler, Joachim Thiery, Uta Ceglarek
    (2018)
    Targeted On-line SPE-LC-MS/MS Assay for the Quantitation of 12 Apolipoproteins from Human Blood
    The American Journal of trorical medicine and hygiene, 18, 3-4
    (Impactfactor: 4,041)
    PDF Download (884 kB, Englisch, 11 Seiten) BibTeX-Ausgabe
  • K. Hohloch, B. Altmann, M. Pfreundschuh, M. Loeffler, N. Schmitz, F. Zettl, M. Ziepert, L. Truemper
    (2018)
    Obesity negatively impacts outcome in elderly female patients with aggressive B-cell lymphomas treated with R-CHOP*: results from prospective trials of the German high grade non-HodgkinÂ’s lymphoma trial group
    British Journal of Hameatology, 180(2), 236-245
    (Impactfactor: 5,67)
    PDF Download (374 kB, Englisch, 10 Seiten) BibTeX-Ausgabe
  • Heike Horn, Christian Kohler, Raphael Witzig, Markus Kreuz, Ellen Leich, Wolfram Klapper, Michael Hummel, Markus Loeffler, Lorenz Trümper, Rainer Spang, Andreas Rosenwald, German Ott
    (2018)
    Gene expression profiling reveals a close relationship between follicular lymphoma grade 3A and 3B, but distinct profiles of follicular lymphoma grade 1 and 2
    Haematolgica, 103(7), 1182-1190
    (Impactfactor: 9,09)
    PDF Download (1,3 MB, Englisch, 9 Seiten) BibTeX-Ausgabe
  • Lasse Jost, Michael Fuchs, Markus Loeffler, Joachim Thiery, Juergen Kratzsch, Thomas Berger, Christoph Engel
    (2018)
    Associations of Sex Hormones and Anthropometry with the Speaking Voice Profile in the Adult General Population
    Journal of Voice, 32(3), 261-272
    (Impactfactor: 1,381)
    PDF Download (1,7 MB, Englisch, 12 Seiten) BibTeX-Ausgabe
  • Jana Kynast, Leonie Lampe, Tobias Luck, Stefan Frisch, Katrin Arélin, Karl-Titus Hoffmann, Markus Loeffler, Steffi G Riedel-Heller, Arno Villringer, Matthias L Schroeter
    (2018)
    White matter hyperintensities associated with small vessel disease impair social cognition beside attention and memory
    Journal of Cerebral Blood Flow & Metabolism, 38(6), 996-1009
    (Impactfactor: 5,081)
    BibTeX-Ausgabe
  • Tobias Luck, Alexander Pabst, Francisca S. Rodriguez, Matthias L. Schroeter, Veronica Witte, Andreas Hinz, Anja Mehnert, Christoph Engel, Markus Loeffler, Joachim Thiery, Arno Villringer, Steffi G. Riedel-Heller
    (2018)
    Age-, sex-, and education-specific norms for an extended CERAD Neuropsychological Assessment Battery—Results from the population-based LIFE-Adult-Study
    Neuropsychology, 32(4), 461-475
    (Impactfactor: 3,286)
    BibTeX-Ausgabe
  • Tobias Luck, Susanne Roehr, Francisca S. Rodriguez, Matthias L. Schroeter, A. Veronica Witte, Andreas Hinz, Anja Mehnert, Christoph Engel, Markus Loeffler, Joachim Thiery, Arno Villringer, Steffi G. Riedel-Heller
    (2018)
    Memory-related subjective cognitive symptoms in the adult population: prevalence and associated factors – results of the LIFE-Adult-Study
    BMC Psychology, 6(1), 1-15
    PDF Download (697 kB, Englisch, 15 Seiten) BibTeX-Ausgabe
  • Shahrzad Kharabian Masouleh, Frauke Beyer, Leonie Lampe, Markus Loeffler, Tobias Luck, Steffi G Riedel-Heller, Matthias L Schroeter, Michael Stumvoll, Arno Villringer, A Veronica Witte
    (2018)
    Gray matter structural networks are associated with cardiovascular risk factors in healthy older adults
    Journal of Cerebral Blood Flow & Metabolism, 38(2), 360-372
    (Impactfactor: 5,081)
    BibTeX-Ausgabe
  • Ulrike Paul, Julia Richter, Christiane Stuhlmann-Laiesz, Markus Kreuz, Inga Nagel, Heike Horn, Annette M. Staiger, Sietse M. Aukema, Michael Hummel, German Ott, Rainer Spang, Andreas Rosenwald, Alfred C. Feller, Sergio Cogliatti, Harald Stein, Martin-Leo Hansmann, Peter Möller, Monika Szczepanowski, Birgit Burkhardt, Michael Pfreundschuh, Norbert Schmitz, Markus Loeffler, Lorenz Trümper, Reiner Siebert, Wolfram Klapper
    (2018)
    Advanced patient age at diagnosis of diffuse large B-cell lymphoma is associated with molecular characteristics including ABC-subtype and high expression of MYC
    Leukemia & Lymphoma, 59(5), 1213-1221
    (Impactfactor: 7,9)
    BibTeX-Ausgabe
  • J Pott, V Schlegel, A Teren, Horn, H Kirsten, C Bluecher, J Kratzsch, M Loeffler, J Thiery, R Burkhardt, M Scholz
    (2018)
    Genetic Regulation of PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) Plasma Levels and Its Impact on Atherosclerotic Vascular Disease Phenotypes.
    Circulation. Genomic and precision medicine, 11(5), e001992
    PDF Download (2,0 MB, Englisch, 33 Seiten) BibTeX-Ausgabe
  • Francisca S. Rodriguez, Matthias L. Schroeter, Katrin Arélin, A. Veronica Witte, Ronny Baber, Ralph Burkhardt, Christoph Engel, Markus Löffler, Joachim Thiery, Arno Villringer, Tobias Luck, Steffi G. Riedel-Heller
    (2018)
    APOE e4-genotype and lifestyle interaction on cognitive performance: Results of the LIFE-Adult-study
    Health psychology, 37(2), 194-205
    (Impactfactor: 3,458)
    BibTeX-Ausgabe
  • Sibylle Schirm, Christoph Engel, Sibylle Loibl, Markus Loeffler, Markus Scholz
    (2018)
    Model‑based optimization of G‑CSF treatment during cytotoxic chemotherapy
    Journal of cancer research and clinical oncology, 144(2), 343-358
    (Impactfactor: 3,503)
    PDF Download (2,1 MB, Englisch, 16 Seiten) BibTeX-Ausgabe
  • Jana Schmidt, Ulrike Guder, Markus Kreuz, Markus Löffler, Wieland Kiess, Christian Hirsch, Dirk Ziebolz, Rainer Haak
    (2018)
    aMMP-8 in correlation to caries and periodontal condition in adolescents—results of the epidemiologic LIFE child study
    Clinical oral investigations, 22(1), 449-460
    (Impactfactor: 2,308)
    PDF Download (821 kB, Englisch, 12 Seiten) BibTeX-Ausgabe
  • Torsten Thalheim, Marianne Quaas, Maria Herberg, Ulf-Dietrich Braumann, Christiane Kerner, Markus Loeffler, Gabriela Aust, Joerg Galle
    (2018)
    Linking stem cell function and growth pattern of intestinal organoids
    Developmental Biology, 433(2), 254-261
    (Impactfactor: 2,944)
    PDF Download (1,3 MB, Englisch, 8 Seiten) BibTeX-Ausgabe
  • Alfred Winter, Sebastian STÄUBERT, Danny Ammon, Stephan Aiche, Oya Beyan, Verena Bischoff, Philipp Daumke, Stefan Decker, Gert Funkat, Jan E. Gewehr, Armin de Greiff, Silke Haferkamp, Udo Hahn, Andreas Henkel, Toralf Kirsten, Thomas Klöss, Jörg Lippert, Matthias LÖBE, Volker Lowitsch, Oliver Maassen, Jens Maschmann, Sven Meister, Rafael Mikolajczyk, Matthias Nüchter, Mathias W. Pletz, Erhard Rahm, Morris Riedel, Kutaiba Saleh, Andreas Schuppert, Stefan Smers, André Stollenwerk, Stefan Uhlig, Thomas Wendt, Sven Zenker, Wolfgang Fleig, Gernot Marx, André Scherag, Markus Löffler
    (2018)
    Smart Medical Information Technology for Healthcare (SMITH)
    Methods Inf Med., 57(S01), 92-105
    (Impactfactor: 1,531)
    PDF Download (472 kB, Englisch, 14 Seiten) BibTeX-Ausgabe
  • Rui Zhang, Frauke Beyer, Leonie Lampe, Tobias Luck, Steffi G. Riedel-Heller, Markus Loeffler, Matthias L. Schroeter, Michael Stumvoll, Arno Villringer, A. Veronica Witte
    (2018)
    White matter microstructural variability mediates the relation between obesity and cognition in healthy adults
    NeuroImage, 172, 239-249
    (Impactfactor: 5,835)
    PDF Download (2,4 MB, Englisch, 11 Seiten) BibTeX-Ausgabe
  • Andrea E. Zuelke, Tobias Luck, Matthias L. Schroeter, A. Veronica Witte, Andreas Hinz, Christoph Engel, Cornelia Enzenbach, Silke Zachariae, Markus Loeffler, Joachim Thiery, Arno Villringer, Steffi G. Riedel-Heller
    (2018)
    The association between unemployment and depression–Results from the population-based LIFE-adult-study
    Journal of affective dissorders, 235, 399-406
    (Impactfactor: 3,432)
    PDF Download (294 kB, Englisch, 8 Seiten) BibTeX-Ausgabe
  • Martin Berg, Michael Fuchs, Kerstin Wirkner, Markus Loeffler, Christoph Engel, Thomas Berger
    (2017)
    The Speaking Voice in the General Population: Normative Data and Associations to Sociodemographic and Lifestyle Factors
    Journal of Voice, 31(2), .e13-257.e24
    (Impactfactor: 1,113)
    PDF Download (1,7 MB, Englisch, 12 Seiten) BibTeX-Ausgabe
  • Hans Binder, Lydia Hopp, Michal R Schweiger, Steve Hoffmann, Frank Jühling, Martin Kerick, Bernd Timmermann, Susann Siebert, Christina Grimm, Lilit Nersisyan, Arsen Arakelyan, Maria Herberg, Peter Buske, Henry Loeffler-Wirth, Maciej Rosolowski, Christoph Engel, Jens Przybilla, Martin Peifer, Nicolaus Friedrichs, Gabriela Moeslein, Margarete Odenthal, Michelle Hussong, Sophia Peters, Stefanie Holzapfel, Jacob Nattermann, Robert Hueneburg, Wolff Schmiegel, Brigitte Royer-Pokora, Stefan Aretz, Michael Kloth, Matthias Kloor, Reinhard Buettner, Jörg Galle, Markus Loeffler
    (2017)
    Genomic and transcriptomic heterogeneity of colorectal tumours arising in Lynch syndrome
    Journal of Pathology, 243, 242-254
    (Impactfactor: 6,894)
    PDF Download (1,8 MB, Englisch, 13 Seiten) BibTeX-Ausgabe
  • Nikolaus Buchmann, Markus Scholz, Christina M. Lill, Ralph Burkhardt, Rahel Eckardt, Kristina Norman, Markus Loeffler, Lars Bertram, Joachim Thiery, Elisabeth Steinhagen-Thiessen, Ilja Demuth
    (2017)
    Association between lipoprotein(a) level and type 2 diabetes: no evidence for a causal role of lipoprotein(a) and insulin
    Acta Diabetol, 54(11), 1031-1038
    (Impactfactor: 2,471)
    PDF Download (770 kB, Englisch, 8 Seiten) BibTeX-Ausgabe
  • Jörg Felsberg, Bettina Hentschel, Kerstin Kaulich, Dorothee Gramatzki, Angela Zacher, Bastian Malzkorn, Marcel Kamp, Michael Sabel, Matthias Simon, Manfred Westphal, Gabriele Schackert, Jörg C. Tonn, Torsten Pietsch, Andreas von Deimling, Markus Loeffler, Guido Reifenberger, Michael Weller
    (2017)
    Epidermal Growth Factor Receptor Variant III (EGFRvIII) Positivity in EGFR-Amplified Glioblastomas: Prognostic Role and Comparison between Primary and Recurrent Tumors
    Clinical Caner Research, 23(22), 6846-6855
    (Impactfactor: 9,619)
    PDF Download (1,1 MB, Englisch, 11 Seiten) BibTeX-Ausgabe
  • Fabian Glock, Mandy Vogel, Stephanie Naumann, Andreas Kuehnapfel, Markus Scholz, Andreas Hiemisch, Toralf Kirsten, Kristin Rieger, Antje Koerner, Markus Loeffler, Wieland Kiess
    (2017)
    Validity and intraobserver reliability of three-dimensional scanning compared with conventional anthropometry for children and adolescents from a population-based cohort study
    81(5), 736-744
    (Impactfactor: 2,882)
    BibTeX-Ausgabe
  • Dorothee Gramatzki, Philipp Kickingereder, Bettina Hentschel, Jörg Felsberg, Ulrich Herrlinger, Gabriele Schackert, Jörg-Christian Tonn, Manfred Westphal, Michael Sabel, Uwe Schlegel, Wolfgang Wick, Torsten Pietsch, Guido Reifenberger, Markus Loeffler, Martin Bendszus, Michael Weller
    (2017)
    Limited role for extended maintenance temozolomide for newly diagnosed glioblastoma
    Neurology, 88(15), 1422-1430
    (Impactfactor: 7,592)
    BibTeX-Ausgabe
  • Andreas Hinz, Heide Glaesmer, Elmar Brähler, Markus Löffler, Christoph Engel, Cornelia Enzenbach, Ulrich Hegerl, Christian Sander
    (2017)
    Sleep quality in the general population: psychometric properties of the Pittsburgh Sleep Quality Index, derived from a German community sample of 9284 people
    Sleep Medicine, 30, 57-63
    (Impactfactor: 3,339)
    PDF Download (207 kB, Englisch, 7 Seiten) BibTeX-Ausgabe
  • Jennifer Junge, Christoph Engel, Mandy Vogel, Stephanie Naumann, Markus Löffler, Joachim Thiery, Jürgen Kratzsch, Wieland Kiess, Antje Körner
    (2017)
    Neck circumference is similarly predicting for impairment of glucose tolerance as classic anthropometric parameters among healthy and obese children and adolescents
    Journal of Pediatric Endocrinolgy and metabolism (JPEM), 30(6), 643-650
    (Impactfactor: 1,233)
    PDF Download (709 kB, Englisch, 8 Seiten) BibTeX-Ausgabe
  • K Keysselt, T Kreutzmann, K Rother, C Kerner, K Krohn, J Przybilla, P Buske, H Löffler-Wirth, M Loeffler, J Galle, G Aust
    (2017)
    Different in vivo and in vitro transformation of intestinal stem cells in mismatch repair deficiency
    Oncogene, 36(19), 2750-2761
    (Impactfactor: 7,519)
    PDF Download (3,7 MB, Englisch, 12 Seiten) BibTeX-Ausgabe
  • Andreas Kuehnapfel, Peter Ahnert, Markus Loeffler, Markus Scholz
    (2017)
    Body surface assessment with 3D laser-based anthropometry: reliability, validation, and improvement of empirical surface formulae
    Eur J Appl Physiol, 117, 371-380
    (Impactfactor: 2,328)
    PDF Download (822 kB, Englisch, 10 Seiten) BibTeX-Ausgabe
  • Franziskus Liem, Ga l Varoquaux, Jana Kynast, Frauke Beyer, Shahrzad Kharabian Masouleh, Julia M. Huntenburg, Leonie Lampe, Mehdi Rahim, Alexandre Abraham, R. Cameron Craddock, Steffi Riedel-Heller, Tobias Luck, Markus Loeffler, Matthias L. Schroeter, Anja Veronica Witte, Arno Villringer, Daniel S. Margulies
    (2017)
    Predicting brain-age from multimodal imaging data captures cognitive impairment
    Neuroimage, 148, 179-188
    (Impactfactor: 5,463)
    PDF Download (1,2 MB, Englisch, 10 Seiten) BibTeX-Ausgabe
  • Henry Loeffler-Wirth, Mandy Vogel, Toralf Kirsten, Fabian Glock, Tanja Poulain, Antje Ko rner, Markus Loeffler, Wieland Kiess, Hans Binder
    (2017)
    Body typing of children and adolescents using 3D-body scanning
    PLOS one, 12(10), 1-11
    (Impactfactor: 2,806)
    PDF Download (7,7 MB, Englisch, 11 Seiten) BibTeX-Ausgabe
  • Antje Löffler, Tobias Luck, Francisca S Then, Claudia Luck-Sikorski, Alexander Pabst, Peter Kovacs, Yvonne Böttcher, Jana Breitfeld, Anke Tönjes, Annette Horstmann, Markus Löffler, Christoph Engel, Joachim Thiery, Arno Villringer, Michael Stumvoll, Steffi G Riedel-Heller
    (2017)
    Effects of psychological eating behaviour domains on the association between socio-economic status and BMI
    Public health nutrion, 20(15), 2706-2712
    (Impactfactor: 2,326)
    PDF Download (515 kB, Englisch, 7 Seiten) BibTeX-Ausgabe
  • Tobias Luck, Francisca S.Then, Matthias L.Schroeter, Veronica Witte, Christoph Engel, Markus Loeffler, Joachim Thiery, Arno Villringer, Steffi G. Riedel-Heller
    (2017)
    Prevalence of DSM-5 Mild Neurocognitive Disorder in Dementia-Free Older Adults: Results of the Population-Based LIFE-Adult-Study
    The American Journal of Geriatric Psychiatry, 25(4), 328-339
    (Impactfactor: 1,302)
    PDF Download (1,9 MB, Englisch, 12 Seiten) BibTeX-Ausgabe
  • Tobias Luck, Francisca S. Then, Christoph Engel, Markus Loeffler, Joachim Thiery, Arno Villringer, Steffi G. Riedel-Heller
    (2017)
    The Prevalence of Current Depressive Symptoms in an Urban Adult Population
    Psychiatrische Praxis, 25/4, 328-339
    (Impactfactor: 3,13)
    PDF Download (9,8 MB, Englisch, 12 Seiten) BibTeX-Ausgabe
  • Michael Pfreundschuh, Niels Murawski, Samira Zeynalova, Marita Ziepert, Markus Loeffler, Matthias Hanel, Judith Dierlamm, Ulrich Keller, Martin Dreyling, Lorenz Truemper, Norbert Frickhofen, Ali-Nuri Hünerlitürkoglu, Norbert Schmitz, Viola Pöschel, Tanja Rixecker, Christian Berdel, Christian Rübe, Gerhard Held, Carsten Zwick
    (2017)
    Optimization of rituximab for the treatment of DLBCL: increasing the dose for elderly male patients
    British Journal of Hameatology, 179(3), 410-420
    (Impactfactor: 5,67)
    PDF Download (336 kB, Englisch, 11 Seiten) BibTeX-Ausgabe
  • Janne Pott, Ralph Burkhardt, Frank Beutner, Katrin Horn, Andrej Teren, Holger Kirsten, Lesca M. Holdt, Gerhard Schuler, Daniel Teupser, Markus Loeffler, Joachim Thiery, Markus Scholz
    (2017)
    Genome-wide meta-analysis identifies novel loci of plaque burden in carotid artery
    Atherosclerosis, 259, 32-40
    (Impactfactor: 3,942)
    PDF Download (780 kB, Englisch, 9 Seiten) BibTeX-Ausgabe
  • Tanja Poulain, Ronny Baber, Mandy Vogel, Diana Pietzner, Toralf Kirsten, Anne Jurkutat, Andreas Hiemisch, Anja Hilbert, Juergen Kratzsch, Joachim Thiery, Michael Fuchs, Christian Hirsch, Franziska G. Rauscher, Markus Loeffler, Antje Koerner, Matthias Nuechter, Wieland Kiess, the LIFE Child study team
    (2017)
    The LIFE Child study: a population-based perinatal and pediatric cohort in Germany
    Eur J Epidemiol, 32(2), 145-158
    (Impactfactor: 7,226)
    PDF Download (568 kB, Englisch, 14 Seiten) BibTeX-Ausgabe
  • Jens Przybilla, Lydia Hopp, Michael Lübbert, Markus Loeffler, Joerg Galle
    (2017)
    Targeting DNA hypermethylation: Computational modeling of DNA demethylation treatment of acute myeloid leukemia
    epigenetics, 12(10), 886-896
    (Impactfactor: 4,394)
    PDF Download (1,7 MB, Englisch, 12 Seiten) BibTeX-Ausgabe
  • Francisca S. Rodriguez, Matthias L. Schroeter, A. Veronica Witte, Christoph Engel, Markus Löffler, Joachim Thiery, Arno Villringer, Tobias Luck, Steffi G. Riedel-Heller
    (2017)
    Could High Mental Demands at Work Offset the Adverse Association Between Social Isolation and Cognitive Functioning? Results of the Population- Based LIFE-Adult-Study
    The American Journal of Geriatric Psychiatry, 25(11), 1258-1269
    (Impactfactor: 2,868)
    PDF Download (445 kB, Englisch, 12 Seiten) BibTeX-Ausgabe
  • Marius Rohde, Bettina R. Bonn, Martin Zimmermann, Jonas Lange, Anja Möricke, Wolfram Klapper, Ilske Oschlies, Monika Szczepanowski, Inga Nagel, Martin Schrappe, Markus Loeffler, Reiner Siebert, Alfred Reiter, Birgit Burkhardt
    (2017)
    Relevance of ID3-TCF3-CCND3 pathway mutations in pediatric aggressive B-cell lymphoma treated according to the non-Hodgkin Lymphoma Berlin-Frankfurt- Münster protocols
    Haematologica , 102(6), 1091-1098
    (Impactfactor: 7,702)
    PDF Download (1,5 MB, Englisch, 8 Seiten) BibTeX-Ausgabe
  • Annette M. Staiger, Marita Ziepert, Heike Horn, David W. Scott, Thomas F.E. Barth, Heinz-Wolfram Bernd, Alfred C. Feller, Wolfram Klapper, Monika Szczepanowski, Michael Hummel, Harald Stein, Dido Lenze, Martin- Leo Hansmann, Sylvia Hartmann, Peter Möller, Sergio Cogliatti, Georg Lenz, Lorenz Trümper, Markus Löffler, Norbert Schmitz, Michael Pfreundschuh, Andreas Rosenwald, German Ott
    (2017)
    Clinical Impact of the Cell-of-Origin Classification and the MYC/BCL2 Dual Expresser Status in Diffuse Large B-Cell Lymphoma Treated Within Prospective Clinical Trials of the German High-Grade Non-Hodgkin’s Lymphoma Study Group
    JOURNAL OF CLINICAL ONCOLOGY, 35(22), 2515-2526
    (Impactfactor: 24,008)
    PDF Download (1,0 MB, Englisch, 19 Seiten) BibTeX-Ausgabe
  • Torsten Thalheim, Maria Herberg, Markus Loeffler, Joerg Galle
    (2017)
    The Regulatory Capacity of Bivalent Genes—A Theoretical Approach
    International Journal o f Molecular Sciences, 18(5), 1-21
    (Impactfactor: 3,226)
    PDF Download (6,4 MB, Englisch, 21 Seiten) BibTeX-Ausgabe
  • Mengyu Wang, Tobias Elze, Dian Li, Neda Baniasadi, Kerstin Wirkner, Toralf Kirsten, Joachim Thiery, Markus Loeffler, Christoph Engel, Franziska G. Rauscher
    (2017)
    Age, ocular magnification, and circumpapillary retinal nerve fiber layer thickness
    Journal of Biomedical Optics, 22(12), 1-19
    (Impactfactor: 2,53)
    PDF Download (1,4 MB, Englisch, 20 Seiten) BibTeX-Ausgabe
  • Thorsten Zenz, Markus Kreuz, Maxi Fuge, Wolfram Klapper, Heike Horn, Annette M. Staiger, Doris Winter, Hanne Helfrich, Jennifer Huellein, Martin-Leo Hansmann, Harald Stein, Alfred Feller, Peter Möller, Norbert Schmitz, Lorenz Trümper, Markus Loeffler, Reiner Siebert, Andreas Rosenwald, German Ott, Michael Pfreundschuh, Stephan Stilgenbauer
    (2017)
    TP53 mutation and survival in aggressive B cell lymphoma
    International Journal of Cancer, 141, 1381-1388
    (Impactfactor: 6,513)
    PDF Download (734 kB, Englisch, 9 Seiten) BibTeX-Ausgabe
  • P Ahnert, P Creutz, M Scholz, H Schütte, C Engel, H Hossain, T Chakraborty, M Bauer, M Kiehntopf, U Völker, S Hammerschmidt, M Loeffler, group. Suttorp N PROGRESS study
    (2016)
    PROGRESS - prospective observational study on hospitalized community acquired pneumonia
    BMC Pulmonary Medicine, 16/1, 1-9
    PDF Download (483 kB, Englisch, 9 Seiten) BibTeX-Ausgabe
  • Frank Bloos, Evelyn Trips, Axel Nierhaus, Josef Briegel, Daren K. Heyland, Ulrich Jaschinski, Onnen Moerer, Andreas Weyland, Gernot Marx, Matthias Gründling, Stefan Kluge, Ines Kaufmann, Klaus Ott, Michael Quintel, Florian Jelschen, Patrick Meybohm, Sibylle Rademacher, Andreas Meier-Hellmann, Stefan Utzolino, Udo X. Kaisers, Christian Putensen, Gunnar Elke, Maximilian Ragaller, Herwig Gerlach, Katrin Ludewig, Michael Kiehntopf, Holger Bogatsch, Christoph Engel, Frank M. Brunkhorst, Markus Loeffler, Konrad Reinhart
    (2016)
    Effect of Sodium Selenite Administration and Procalcitonin-Guided Therapy on Mortality in Patients With Severe Sepsis or Septic Shock: A Randomized Clinical Trial
    JAMA , 176(9), 1266-1276
    (Impactfactor: 14)
    PDF Download (433 kB, Englisch, 11 Seiten) BibTeX-Ausgabe
  • SepNet Critical Care Trials Group, Bogatsch H, Engel C, Löffler M
    (2016)
    Incidence of severe sepsis and septic shock in German intensive care units: the prospective, multicentre INSEP study
    Intensive Care Med, 42, 1980-1989
    (Impactfactor: 10,125)
    PDF Download (915 kB, Englisch, 10 Seiten) BibTeX-Ausgabe
  • Kebria Hezaveh, Andreas Kloetgen, Stephan H Bernhart, Kunal Das Mahapatra, Dido Lenze, Julia Richter, Andrea Haake, Anke K Bergmann, Benedikt Brors, Birgit Burkhardt, Alexander Claviez, Hans G Drexler, Roland Eils, Siegfried Haas, Steve Hoffmann, Dennis Karsch, Wolfram Klapper, Kortine Kleinheinz, Jan Korbel, Helene Kretzmer, Markus Kreuz, Ralf Küppers, Chris Lawerenz, Ellen Leich, Markus Loeffler, Luisa Mantovani-Loeffler, Cristina López, Alice C McHardy, Peter Möller, Marius Rohde, Philip Rosenstiel, Andreas Rosenwald, Markus Schilhabel, Matthias Schlesner, Ingrid Scholz, Peter F Stadler, Stephan Stilgenbauer, Stéphanie Sungalee, Monika Szczepanowski, Lorenz Trümper, Marc A Weniger, Reiner Siebert, Arndt Borkhardt, Michael Hummel, Jessica I. Hoell
    (2016)
    Alterations of microRNA and microRNA-regulated messenger RNA expression in germinal center B-cell lymphomas determined by integrative sequencing analysis
    Haematologica, 101(11), 1380-1389
    (Impactfactor: 6,671)
    PDF Download (1,7 MB, Englisch, 10 Seiten) BibTeX-Ausgabe
  • Karin Hohloch, Samira Zeynalova, Björn Chapuy, Michael Pfreundschuh, Markus Loeffler, Marita Ziepert, Alfred C. Feller, Lorenz Trümper, Dirk Hasenclever, Gerald Wulf, Norbert Schmitz
    (2016)
    Modified BEAM with triple autologous stem cell transplantation for patients with relapsed aggressive non-Hodgkin lymphoma
    Annals of Hematology, 95(7), 1121-1128
    (Impactfactor: 3,022)
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  • Didier Keh, Evelyn Trips Gernot Marx, Stefan P. Wirtz, Emad Abduljawwad, Sven Bercker, Holger Bogatsch, Josef Briegel, Christoph Engel, Herwig Gerlach, MBA Anton Goldmann, Sven-Olaf Kuhn, Lars Hüter, Andreas Meier-Hellmann, Axel Nierhaus, Stefan Kluge, Josefa Lehmke, Markus Loeffler, Michael Oppert, Kerstin Resener, Dirk Schädler, Tobias Schuerholz, Philipp Simon, NorbertWeiler, AndreasWeyland, Konrad Reinhart, Frank M. Brunkhorst
    (2016)
    Effect of Hydrocortisone on Development of Shock Among Patients With Severe Sepsis The HYPRESS Randomized Clinical Trial
    JAMA, 316(17), 1775-1785
    (Impactfactor: 37,684)
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  • M Kiechle, C Engel, A Berling, K Hebestreit, SC Bischoff, R Dukatz, M Siniatchkin, K Pfeifer, S Grill, M Yahiaoui-Doktor, E Kirsch, U Niederberger, U Enders, M Löffler, A Meindl, K Rhiem, R Schmutzler, N Erickson, M Halle
    (2016)
    Effects of lifestyle intervention in BRCA1/2 mutation carriers on nutrition, BMI, and physical fitness (LIBRE study): study protocol for a randomized controlled trial
    Trials, 1-9
    PDF Download (536 kB, Englisch, 9 Seiten) BibTeX-Ausgabe
  • Marion Kiechle, Christoph Engel, Anika Berling, Katrin Hebestreit, Stephan Bischoff, Ricarda Dukatz, Wolf-Dieter Gerber, Michael Siniatchkin, Katharina Pfeifer, Sabine Grill, Maryam Yahiaoui-Doktor, Ellen Kirsch, Uwe Niederberger, Nicole Marter, Ute Enders, Markus Löffler, Alfons Meindl, Kerstin Rhiem, Rita Schmutzler, Nicole Erickson, Martin Halle
    (2016)
    Lifestyle intervention in BRCA1/2 mutation carriers: study protocol for a prospective, randomized, controlled clinical feasibility trial (LIBRE-1 study)
    Pilot Feasibility Stud. , 2:74, 1-10
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  • Michael Kloth, Vanessa Ruesseler, Christoph Engel, Katharina Koenig, Martin Peifer, Erika Mariotti, Helen Kuenstlinger, Alexandra Florin, Ursula Rommerscheidt-Fuss, Ulrike Koitzsch, Claudia Wodtke, Frank Ueckeroth, Stefanie Holzapfel, Stefan Aretz, Peter Propping, Markus Loeffler, Sabine Merkelbach-Bruse, Margarete Odenthal, Nicolaus Friedrichs, Lukas Carl Heukamp, Thomas Zander, Reinhard Buettner
    (2016)
    Activating ERBB2/HER2 mutations indicate susceptibility to pan-HER inhibitors in Lynch and Lynch-like colorectal cancer
    Gut, 65(8), 1296-1305
    (Impactfactor: 14,921)
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  • K. Koch, E. Hoster, M. Ziepert, M. Unterhalt, G. Ott, A. Rosenwald, L. Hansmann M., W. Bernd, H. Stein, V. Pöschel, M. Dreyling, L. Trümper, M. Löffler, N. Schmitz, W. Hiddemann, M. Pfreundschuh, W. Klapper
    (2016)
    Clinical, pathological and genetic features of follicular lymphoma grade 3A: a joint analysis of the German low-grade and high-grade lymphoma study groups GLSG and DSHNHL
    Annals of Hematology, 27/7, 1323-1329
    (Impactfactor: 9,269)
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  • Andreas Kuehnapfel, Peter Ahnert, Markus Loeffler, Anja Broda, Markus Scholz
    (2016)
    Reliability of 3D laser-based anthropometry and comparison with classical anthropometry
    Scientific Reports, 6, 26672
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  • H Löffler-Wirth, E Willscher, P Ahnert, K Wirkner, C Engel, M Loeffler, H Binder
    (2016)
    Novel Anthropometry Based on 3D-Bodyscans Applied to a Large Population Based Cohort
    PLoS One, 11(7), 1-20
    (Impactfactor: 3,057)
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  • Sibylle Schirm, Peter Ahnert, Sandra Wienhold, Holger Mueller-Redetzky, Geraldine Nouailles-Kursar, Markus Loeffler, Martin Witzenrath, Markus Scholz
    (2016)
    A Biomathematical Model of Pneumococcal Lung Infection and Antibiotic Treatment in Mice
    PLoS One, 11/5, e0156047
    (Impactfactor: 3,057)
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  • Norbert Schmitz, Samira Zeynalova, Maike Nickelsen, Roopesh Kansara, Diego Villa, Laurie H. Sehn, Bertram Glass, David W. Scott, Randy D. Gascoyne, Joseph M. Connors, Marita Ziepert, Michael Pfreundschuh, Markus Loeffler, Kerry J. Savage
    (2016)
    CNS International Prognostic Index: A Risk Model for CNS Relapse in Patients With Diffuse Large B-Cell Lymphoma Treated With R-CHOP
    JOURNAL OF CLINICAL ONCOLOGY, 34 (26), 3150-3156
    (Impactfactor: 20,982)
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  • Anton Shostak, Bianca Ruppert, Nati Ha, Philipp Bruns, Umut H. Toprak, ICGC MMML-Seq Project, Roland Eils, Matthias Schlesner, Axel Diernfellner, Michael Brunner, Chris Lawerenz, Peter Lichter, Bernhard Radlwimmer, Jürgen Eils, Benedikt Brors, Sylwester Radomski, Ingrid Scholz, Gesine Richter, Reiner Siebert, Susanne Wagner, Andrea Haake, Julia Richter, Sietse Aukema, Ole Ammerpohl, Christina Lopez, Inga Nagel, Inga Vater, Rabea Wagner, Christoph Borst, Siegfried Haas, Marius Rohde, Birgit Burkhardt, Jasmin Lisfeld, Alexander Claviez, Martin Dreyling, Sonja Eberth, Lorenz Trümper, Dieter Kube, Christina Stadler, Hermann Einsele, Norbert Frickhofen, Martin-Leo Hansmann, Dennis Karsch, Michael Kneba, Luisa Mantovani-Löffler, Peter Staib, Stephan Stilgenbauer, German Ott, Ralf Küppers, Marc Weniger, Michael Hummel, Dido Lenze, Monika Szczepanowski, Wolfram Klapper, Ulrike Kostezka, Peter Möller, Andreas Rosenwald, Ellen Leich, Jordan Pischimariov, Vera Binder, Arndt Borkhardt, Kebria Hezaveh, Jessica Hoell, Philip Rosenstiel, Markus Schilhabel, Stefan Schreiber, Stephan H. Bernhart, Gero Doose, Steve Hoffmann, Helene Kretzmer, David Langenberger, Hans Binder, Lydia Hopp, Markus Kreuz, Markus Loeffler, Maciej Rosolowski, Jan Korbel, Stefanie Sungalee, Peter F. Stadler, Thorsten Zenz
    (2016)
    MYC/MIZ1-dependent gene repression inversely coordinates the circadian clock with cell cycle and proliferation
    Nature Communications, 7, 1-11
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  • Janek Spada, Markus Scholz, Holger Kirsten, Tilman Hensch, Katrin Horn, PH I L I P P E JAWINSKI, Christine Ulke, Ralph Burkhardt, Kerstin Wirkner, Markus Loeffler, Ulrich Hegerl, Christian Sander
    (2016)
    Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study
    European Sleep Research Society, 25(6), 690-701
    (Impactfactor: 3,093)
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  • Hendrik G. Stunnenberg, Martin Hirst, Markus Loeffler
    (2016)
    The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery
    Cell, 167(5), 1145-1149
    (Impactfactor: 28,71)
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  • Andrej Teren, Frank Beutner, Kerstin Wirkner, Markus Löffler, Markus Scholz
    (2016)
    Relationship Between Determinants of Arterial Stiffness Assessed by Diastolic and Suprasystolic Pulse Oscillometry
    Medicine (Baltimore), 95(10), 1-10
    (Impactfactor: 1,206)
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  • Andrej Teren, Silke Zachariae, Frank Beutner, Romy Ubrich, Marcus Sandri, Christoph Engel, Markus Löffler, Stephan Gielen
    (2016)
    Incremental value of Veterans Specific Activity Questionnaire and the YMCA-step test for the assessment of cardiorespiratory fitness in population-based studies
    European Journal of Preventive Cardiology, 23(11), 1221-1227
    (Impactfactor: 3,361)
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  • Torsten Thalheim, Peter Buske, Jens Przybilla, Karen Rother, Markus Loeffler, Joerg Galle
    (2016)
    Stem cell competition in the gut: insights from multi-scale computational modelling
    J R Soc Interface , 13(121), 1-10
    (Impactfactor: 3,818)
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  • A Dietz, M Loeffler, M Rosolowski, M Kreuz, F Lordick, M Knödler, C Mozet, G Wichmann
    (2015)
    Gene expression analyses and their possible clinical benefit in head and neck cancer
    HNO, 63(11), 773-785
    (Impactfactor: 0,58)
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  • G Doose, A Haake, SH Bernhart, C López, S Duggimpudi, F Wojciech, AK Bergmann, A Borkhardt, B Burkhardt, A Claviez, L Dimitrova, S Haas, JI Hoell, M Hummel, D Karsch, W Klapper, K Kleo, H Kretzmer, M Kreuz, R Küppers, C Lawerenz, D Lenze, M Loeffler, L Mantovani-Löffler, P Moller, G Ott, J Richter, M Rohde, P Rosenstiel, A Rosenwald, M Schilhabel, M Schneider, I Scholz, S Stilgenbauer, HG Stunnenberg, M Szczepanowski, L Trümper, MA Weniger, ICGC MMML-Seq Consortium, S Hoffmann, R Siebert, al. et
    (2015)
    MINCR is a MYC-induced lncRNA able to modulate MYC's transcriptional network in Burkitt lymphoma cells
    PNAS (Proc Natl Acad Sci USA), 112(38), E5261-5270, DOI: 10.1073/pnas.
    (Impactfactor: 9,674)
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  • H Horn, M Ziepert, M Wartenberg, AM Staiger, TF Barth, HW Bernd, AC Feller, W Klapper, C Stuhlmann-Laeisz, M Hummel, H Stein, D Lenze, S Hartmann, ML Hansmann, P Moller, S Cogliatti, M Pfreundschuh, L Trümper, M Loeffler, B Glass, N Schmitz, G Ott, A Rosenwald
    (2015)
    Different biological risk factors in young poor-prognosis and elderly patients with diffuse large B-cell lymphoma
    LEUKEMIA (Nature), 29(7), 1564-1570
    (Impactfactor: 10,431)
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  • H Kirsten, H Al-Hasani, L Holdt, A Gross, F Beutner, K Krohn, K Horn, P Ahnert, R Burkhardt, K Reiche, J Hackermüller, M Löffler, D Teupser, J Thiery, M Scholz
    (2015)
    Dissecting the genetics of the human transcriptome identifies novel trait-related trans-eQTLs and corroborates the regulatory relevance of non-protein coding loci
    HUMAN MOLECULAR GENETICS, 24(16), 4746-4763
    (Impactfactor: 6,393)
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  • H Kretzmer, SH Bernhart, W Wang, A Haake, MA Weniger, A Bergmann, MJ Betts, E Carrillo-de-Santa-Pau, G Doose, J Gutwein, J Richter, V Hovestadt, B Huang, D Rico, F Jühling, J Kolarova, Q Lu, C Otto, R Wagener, J Arnolds, B Burkhardt, A Claviez, HG Drexler, S Eberth, R Eils, P Flicek, S Haas, M Hummel, D Karsch, HH Kerstens, W Klapper, M Kreuz, C Lawerenz, D Lenze, M Loeffler, C López, RA MacLeod, JH Martens, M Kulis, JI Martín-Subero, P Moller, I Nagel, S Picelli, I Vater, M Rohde, P Rosenstiel, M Rosolowski, et al.
    (2015)
    DNA methylome analysis in Burkitt and follicular lymphomas identifies differentially methylated regions linked to somatic mutation and transcriptional control
    NATURE GENETICS, 47(11), 1316-1325
    (Impactfactor: 29,352)
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  • M Loeffler, C Engel, P Ahnert, D Alfermann, K Arelin, R Baber, F Beutner, H Binder, E Brähler, R Burkhardt, U Ceglarek, C Enzenbach, M Fuchs, H Glaesmer, F Girlich, A Hagendorff, M Häntzsch, U Hegerl, S Henger, T Hensch, A Hinz, V Holzendorf, D Husser, A Kersting, A Kiel, T Kirsten, J Kratzsch, K Krohn, T Luck, S Melzer, J Netto, M Nüchter, M Raschpichler, FG Rauscher, SG Riedel-Heller, C Sander, M Scholz, P Schönknecht, ML Schroeter, JC Simon, R Speer, J Stäker, R Stein, Y Stöbel-Richter, M Stumvoll, A Tarnok, A Teren, D Teupser, FS Then, A Tönjes, R Treudler, A Villringer, A Weissgerber, P Wiedemann, S Zachariae, K Wirkner, J Thiery
    (2015)
    The LIFE-Adult-Study: objectives and design of a population-based cohort study with 10,000 deeply phenotyped adults in Germany
    BMC PUBLIC HEALTH, 15(1), 691
    (Impactfactor: 2,264)
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  • M Loeffler, M Kreuz, A Haake, D Hasenclever, H Trautmann, C Arnold, K Winter, K Koch, W Klapper, R Scholtysik, M Rosolowski, S Hoffmann, O Ammerpohl, M Szczepanowski, D Herrmann, R Kueppers, C Pott, R Siebert
    (2015)
    Genomic and epigenomic co-evolution in follicular lymphomas.
    LEUKEMIA (Nature), 29(2), 456-463
    (Impactfactor: 10,431)
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  • A Löffler, T Luck, FS Then, C Sikorski, P Kovacs, Y Böttcher, J Breitfeld, A Tönjes, A Horstmann, M Löffler, C Engel, J Thiery, A Villringer, M Stumvoll, SG Riedel-Heller
    (2015)
    Eating Behaviour in the General Population: An Analysis of the Factor Structure of the German Version of the Three-Factor-Eating-Questionnaire (TFEQ) and Its Association with the Body Mass Index
    PLOS ONE, 10(7),
    (Impactfactor: 3,234)
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  • A Löffler, T Luck, FS Then, M Luppa, C Sikorski, P Kovacs, A Tönjes, Y Böttcher, J Breitfeld, A Horstmann, M Löffler, C Engel, J Thiery, M Stumvoll, SG Riedel-Heller
    (2015)
    Age- and gender-specific norms for the German version of the Three-Factor Eating-Questionnaire (TFEQ)
    APPETITE, 91, 241-247
    (Impactfactor: 2,691)
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  • T Luck, FS Then, M Luppa, ML Schroeter, K Arelin, R Burkhardt, J Thiery, M Löffler, A Villringer, SG Riedel-Heller
    (2015)
    Association of the apolipoprotein E genotype with memory performance and executive functioning in cognitively intact elderly
    NEUROPSYCHOBIOLOGY, 29(3), 382-387
    (Impactfactor: 3,269)
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  • S Melzer, S Zachariae, J Bocsi, C Engel, M Löffler, A Tarnok
    (2015)
    Reference intervals for leukocyte subsets in adults: Results from a population-based study using 10-color flow cytometry
    CYTOMETRY PART B: CLINICAL CYTOMETRY , 88(4), 1397-1407
    (Impactfactor: 2,398)
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  • R Scholtysik, M Kreuz, M Hummel, M Rosolowski, M Szczepanowski, W Klapper, M Loeffler, L Trümper, R Siebert, R Kueppers
    (2015)
    Characterization of genomic imbalances in diffuse large B-cell lymphoma by detailed SNP-chip analysis.
    INTERNATIONAL JOURNAL OF CANCER, 136(5), 1033-1042
    (Impactfactor: 5,007)
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  • R Wagener, SM Aukema, M Schlesner, A Haake, B Burkhardt, A Claviez, HG Drexler, M Hummel, M Kreuz, M Loeffler, M Rosolowski, C López, P Moller, J Richter, M Rohde, MJ Betts, RB Russell, SH Bernhart, S Hoffmann, P Rosenstiel, M Schilhabel, M Szczepanowski, L Trümper, W Klapper, R Siebert, im Auftrag Deutsche Krebshilfe
    (2015)
    The PCBP1 gene encoding poly(rC) binding protein I is recurrently mutated in Burkitt lymphoma
    GENES, CHROMOSOMES & CANCER, 54(9), 555-564
    (Impactfactor: 4,041)
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  • M Weller, RG Weber, E Willscher, V Riehmer, B Hentschel, M Kreuz, J Felsberg, U Beyer, H Löffler-Wirth, K Kaulich, JP Steinbach, C Hartmann, D Gramatzki, J Schramm, M Westphal, G Schackert, M Simon, T Martens, J Boström, C Hagel, M Sabel, D Krex, JC Tonn, W Wick, S Noell, U Schlegel, B Radlwimmer, T Pietsch, M Loeffler, A von Deimling, H Binder, G Reifenberger
    (2015)
    Molecular classification of diffuse cerebral WHO grade II/III gliomas using genome- and transcriptome-wide profiling improves stratification of prognostically distinct patient groups
    ACTA NEUROPATHOLOGICA, 129(5), 679-693
    (Impactfactor: 10,762)
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  • G Wichmann, M Rosolowski, K Krohn, M Kreuz, A Boehm, A Reiche, U Scharrer, D Halama, J Bertolini, U Bauer, D Holzinger, M Pawlita, J Hess, C Engel, D Hasenclever, M Scholz, P Ahnert, H Kirsten, A Hemprich, C Wittekind, O Herbarth, F Horn, A Dietz, M Loeffler, Leipzig Head and Neck Group (LHNG)
    (2015)
    The role of HPV RNA transcription, immune response-related gene expression and disruptive TP53 mutations in diagnostic and prognostic profiling of head and neck cancer
    INTERNATIONAL JOURNAL OF CANCER, 137(12), 2846-2857
    (Impactfactor: 5,085)
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  • SM Aukema, M Kreuz, CW Kohler, M Rosolowski, D Hasenclever, M Hummel, R Küppers, D Lenze, G Ott, C Pott, J Richter, A Rosenwald, M Szczepanowski, C Schwaenen, H Stein, H Trautmann, S Wessendorf, L Truemper, M Loeffler, R Spang, PM Kluin, W Klapper, R Siebert
    (2014)
    Biologic characterization of adult MYC-translocation positive mature B-cell lymphomas other than molecular Burkitt lymphoma.
    Haematologica, 99(4), 726-735
    (Impactfactor: 5,868)
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  • P Buske, J Przybilla, M Loeffler, J Galle
    (2014)
    The intestinal stem cell niche: a computational tissue approach
    Biochemical Society Transactions, 42(3), 671-677
    (Impactfactor: 3,238)
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  • G Held, N Murawski, M Ziepert, J Fleckenstein, V Pöschel, C Zwick, J Bittenbring, M Hänel, S Wilhelm, J Schubert, N Schmitz, M Löffler, C Rübe, M Pfreundschuh
    (2014)
    Role of Radiotherapy to Bulky Disease in Elderly Patients With Aggressive B-Cell Lymphoma.
    Journal of Clinical Oncology, 32(11), 1112-1121
    (Impactfactor: 17,96)
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  • K Hohloch, S Zeynalova, G Held, M Ziepert, M Loeffler, G Wulf, N Schmitz, M Pfreundschuh, L Truemper
    (2014)
    Excellent outcome of young adults with aggressive non-Hodgkin lymphomas treated with CHOP-like regimens.
    Leukemia, 28(11), 2260-2263
    (Impactfactor: 9,379)
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  • M Loeffler
    (2014)
    The German National Cohort: aims, study design and organization.
    Eur J Epidemiology , 29(5), 371-382
    (Impactfactor: 5,147)
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  • J Przybilla, T Rohlf, M Loeffler, J Galle
    (2014)
    Understanding epigenetic changes in aging stem cells - a computational model approach.
    Aging Cell, 13(2), 320-328
    (Impactfactor: 5,939)
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  • G Reifenberger, RG Weber, V Riehmer, K Kaulich, E Willscher, H Wirth, J Gietzelt, B Hentschel, M Westphal, M Simon, G Schackert, J Schramm, J Matschke, MC Sabel, D Gramatzki, J Felsberg, C Hartmann, JP Steinbach, U Schlegel, W Wick, B Radlwimmer, T Pietsch, JC Tonn, A von Deimling, H Binder, M Weller, M Loeffler
    (2014)
    Molecular characterization of long-term survivors of glioblastoma using genome- and transcriptome-wide profiling.
    International Journal of Cancer, 135(8), 1822-1831
    (Impactfactor: 5,007)
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  • T Reithmeier, A Kuzeawu, B Hentschel, M Loeffler, M Trippel, G Nikkhah
    (2014)
    Retrospective analysis of 104 histologically proven adult brainstem gliomas: clinical symptoms, therapeutic approaches and prognostic factors.
    BMC Cancer , 14(1), 115
    (Impactfactor: 3,319)
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  • V Riehmer, J Gietzelt, U Beyer, B Hentschel, M Westphal, G Schackert, MC Sabel, B Radlwimmer, T Pietsch, G Reifenberger, M Weller, RG Weber, M Loeffler
    (2014)
    Genomic profiling reveals distinctive molecular relapse patterns in IDH1/2 wild-type glioblastoma.
    Genes Chromosomes Cancer , 53(7), 589-605
    (Impactfactor: 3,836)
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  • I Salaverria, I Martin-Guerrero, R Wagener, M Kreuz, CW Kohler, JC Richter, B Pienkowska-Grela, P Adam, B Burkhardt, A Claviez, C Damm-Welk, HG Drexler, M Hummel, ES Jaffe, R Küppers, C Lefebvre, J Lisfeld, M Löffler, RAF Macleod, I Nagel, I Oschlies, M Rosolowski, RB Russell, G Rymkiewicz, D Schindler, M Schlesner, R Scholtysik, C Schwaenen, R Spang, M Szczepanowski, L Trümper, I Vater, S Wessendorf, W Klapper, R Siebert
    (2014)
    A recurrent 11q aberration pattern characterizes a subset of MYC-negative high-grade B-cell lymphomas resembling Burkitt lymphoma:
    blood, 123(8), 1187-1198
    (Impactfactor: 9,775)
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  • S Schirm, C Engel, M Loeffler, M Scholz
    (2014)
    Modelling chemotherapy effects on granulopoiesis.
    BMC Syst Biol, 8(1), 138
    (Impactfactor: 2,853)
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  • S Schirm, C Engel, M Loeffler, M Scholz
    (2014)
    A combined model of human erythropoiesis and granulopoiesis under growth factor and chemotherapy treatment.
    Schirm et al. Theoretical Biology and Medical Modelling , 11, 24
    (Impactfactor: 1,265)
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  • V Steinke, S Holzapfel, M Loeffler, E Holinski-Feder, M Morak, HK Schackert, H Goergens, C Pox, B Royer-Pokora, M von Knebel-Doeberitz, R Buettner, P Propping, C Engel
    (2014)
    Evaluating the performance of clinical criteria for predicting mismatch repair gene mutations in Lynch syndrome: A comprehensive analysis of 3,671 families.
    International Journal of Cancer, 135(1), 69-77
    (Impactfactor: 5,007)
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  • FS Then, T Luck, M Luppa, K Arelin, ML Schroeter, C Engel, M Loeffler, J Thiery, A Villringer, SG Riedel-Heller
    (2014)
    Association between mental demands at work and cognitive functioning in the general population - results of the health study of the Leipzig research center for civilization diseases (LIFE).
    J Occup Med Toxicol, 9, 23
    (Impactfactor: 1,226)
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  • M Weller, K Kaulich, B Hentschel, J Felsberg, D Gramatzki, T Pietsch, M Simon, M Westphal, G Schackert, JC Tonn, A von Deimling, T Davis, WA Weiss, M Loeffler, G Reifenberger
    (2014)
    Assessment and prognostic significance of the epidermal growth factor receptor vIII mutation in glioblastoma patients treated with concurrent and adjuvant temozolomide radiochemotherapy.
    Int J Cancer , 134(10), 2437-2447
    (Impactfactor: 5,007)
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  • V Winkler, M Leitzmann, N Obi, W Ahrens, T Edinger, G Giani, J Linseisen, M Loeffler, K Michels, U Noethlings, SA Schipf, A Kluttig, HE Wichmann, B Hoffmann, KH Joeckel, H Becher
    (2014)
    Response in individuals with and without foreign background and application to the National Cohort in Germany: which factors have an effect?
    Int J Public Health , 59(3), 555-563
    (Impactfactor: 1,966)
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  • S. M. Aukema, M. Kreuz, C. W. Kohler, M. Rosolowski, D. Hasenclever, M. Hummel, R. Kuppers, D. Lenze, G. Ott, C. Pott, J. Richter, A. Rosenwald, M. Szczepanowski, C. Schwaenen, H. Stein, H. Trautmann, S. Wessendorf, L. Trümper, M. Loeffler, R. Spang, P. M. Kluin, W. Klapper, R. Siebert
    (2013)
    Biologic characterization of adult MYC-translocation positive mature B-cell lymphomas other than molecular Burkitt lymphoma.
    Haematologica., Epub ahead of print,
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  • C. Binder, M. Ziepert, M. Pfreundschuh, U. Dührsen, H. Eimermacher, A. Aldaoud, A. Rosenwald, M. Loeffler, N. Schmitz, L. Truemper
    (2013)
    CHO(E)P-14 followed by alemtuzumab consolidation in untreated peripheral T cell lymphomas: final analysis of a prospective phase II trial.
    Ann Hematol., Vol. 92 (11), 1521-1528
    (Impactfactor: 2,866)
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  • F. Edelmann, R. Wachter, A.G. Schmidt, E. Kraigher-Krainer, C. Colantonio, W. Kamke, A. Duvinage, R. Stahrenberg, K. Durstewitz, M. Löffler, H-D. Düngen, C. Tschöpe, C. Hermann-Lingen, M. Halle, G. Hasenfuss, G. Gelbrich, B. Pieske
    (2013)
    Effect of spironolactone on diastolic function and exercise capacity in patients with heart failure with preserved ejection fraction: the Aldo-DHF randomized controlled trial.
    JAMA., Vol. 309 (8), 781-791
    (Impactfactor: 29,978)
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  • G. Elke, E. Kuhnt, M. Ragaller, D. Schädler, I. Frerichs, F. M. Brunkhorst, M. Löffler, K. Reinhart, N. Weiler
    (2013)
    Enteral nutrition is associated with improved outcome in patients with severe sepsis : A secondary analysis of the VISEP trial
    Med Klin Intensivmed Notfmed., Vol. 108 (3), 223-233
    PDF Download (588 kB, Englisch, 11 Seiten) BibTeX-Ausgabe
  • I. Glauche, L. Bystrykh, C. Eaves, I. Roeder, other participants, C. Baum, M. Brugman, L. Bystrykh, KA. de Carvalho, K. Cornils, C. Eaves, B. Fehse, C. Florian, J. Galle, H. Geiger, S. Gerdes, I. Glauche, J. Grosselin, T. Grinenko, G. de Haan, D. Knapp, D. von Laer, P. Leboulch, M. Loeffler, R. Lu, U. Modlich, P. Buske, I. Roeder, M. Schmidt, A. Schwarzer, E. Shapiro, L. Thielecke, A. Traulsen, E. Verovskaya, C. Waskow, M. Wermke, B. Werner
    (2013)
    Stem cell clonality -- theoretical concepts, experimental techniques, and clinical challenges.
    Blood Cells, Molecules and Diseases, Vol. 50 (4), 232-240
    (Impactfactor: 2,259)
    PDF Download (306 kB, Englisch, 9 Seiten) BibTeX-Ausgabe
  • C. Hartmann, B. Hentschel, M. Simon, M. Westphal, G. Schackert, J. C. Tonn, M. Loeffler, G. Reifenberger, T. Pietsch, A. von Deimling, M. Weller
    (2013)
    Long-Term Survival in Primary Glioblastoma With Versus Without Isocitrate Dehydrogenase Mutations.
    Clin Cancer Res., Vol. 19 (18), 5146-5157
    (Impactfactor: 7,837)
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  • Oliver Heese, Eva Vogeler, Tobias Martens, Oliver Schnell, Jörg-Christian Tonn, Matthias Simon, Johannes Schramm, Dietmar Krex, Gabriele Schackert, Thomas Reithmeier, Guido Nikkhah, Michael Sabel, Hans-Jakob Steiger, Uwe Schlegel, Markus Löffler, Michael Weller, Manfred Westphal
    (2013)
    End-of-life caregivers' perception of medical and psychological support during the final weeks of glioma patients: a questionnaire-based survey.
    Neuro Oncol., Vol. 15 (9), 1251-1256
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  • Heike Horn, Marita Ziepert, Claudia Becher, Thomas F. E. Barth, Heinz-Wolfram Bernd, Alfred C. Feller, Wolfram Klapper, Michael Hummel, Harald Stein, Martin-Leo Hansmann, Christopher Schmelter, Peter Möller, Sergio Cogliatti, Michael Pfreundschuh, Norbert Schmitz, Lorenz Trümper, Reiner Siebert, Markus Loeffler, Andreas Rosenwald, German Ott
    (2013)
    MYC status in concert with BCL2 and BCL6 expression predicts outcome in diffuse large B-cell lymphoma
    Blood Journal, Vol. 121 (12), 2253-2263
    (Impactfactor: 9,06)
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  • Matthias Horn, Ingmar Glauche, Martin C. Müller, Rüdiger Hehlmann, Andreas Hochhaus, Markus Loeffler, Ingo Roeder
    (2013)
    Model-based decision rules reduce the risk of molecular relapse after cessation of tyrosine kinase inhibitor therapy in chronic myeloid leukemia
    Blood., Vol. 121 (2), 378-384
    (Impactfactor: 9,06)
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  • Axel Krinner, Ingo Roeder, Markus Loeffler, Markus Scholz
    (2013)
    Merging concepts - coupling an agent-based model of hematopoietic stem cells with an ODE model of granulopoiesis.
    BMC Syst Biol., Vol. 7 (1), 117-137
    (Impactfactor: 2,982)
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  • Maciej Rosolowski, Jürgen Läuter, Dmitriy Abramov, Hans G. Drexler, Michael Hummel, Wolfram Klapper, Roderick A.F. MacLeod, Shoji Pellissery, Friedemann Horn, Reiner Siebert, Markus Loeffler
    (2013)
    Massive transcriptional perturbation in subgroups of diffuse large B-cell lymphomas.
    PLoS One., Vol. 8 (11), e76287
    (Impactfactor: 3,73)
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  • D. Schädler, G. Elke, C. Engel, H. Bogatsch, I. Frerichs, R. Kuhlen, R. Rossaint, M. Quintel, J. Scholz, F. M. Brunkhorst, M. Loeffler, K. Reinhart, N. Weiler
    (2013)
    Ventilatory strategies in septic patients : Results from a nationwide observational trial.
    Anaesthesist., Vol. 62 (1), 27-33
    (Impactfactor: 0,847)
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  • Birgit Schif, Jochen K. Lennerz, Christian W. Kohler, Stefan Bentink, Markus Kreuz, Ingo Melzner, Olga Ritz, Lorenz Trümper, Markus Loeffler, Rainer Spang, Peter Möller
    (2013)
    SOCS1 Mutation Subtypes Predict Divergent Outcomes in Diffuse Large B-Cell Lymphoma (DLBCL) Patients
    Oncotarget., Vol. 4 (1), 35-47
    (Impactfactor: 6,636)
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  • Sibylle Schirm, Christoph Engel, Markus Loeffler, Markus Scholz
    (2013)
    A biomathematical model of human erythropoiesis under erythropoietin and chemotherapy administration.
    PLOS ONE, Vol. 8 (6), e65630
    (Impactfactor: 3,73)
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  • Andrej Teren, Frank Beutner, Kerstin Wirkner, Markus Loeffler, Markus Scholz
    (2013)
    Validity, intra- and inter-observer reliability of automated devices for the assessment of ankle brachial index using photo-plethysmography.
    BMC Cardiovasc Disord. , Vol. 13, 81-88
    (Impactfactor: 1,457)
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  • A. Weimann, B. R. Kern, M. Löffler, A. Sablotzki, F. Thiele, F. M. Brunkhorst
    (2013)
    Enrolment of intensive care patients in clinical studies : Ethical, legal and organizational problems from an interdisciplinary point of view.
    Med Klin Intensivmed Notfmed., Vol. 108 (4), 303-310
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  • W. Wick, C. Meisner, B. Hentschel, M. Platten, A. Schilling, B. Wiestler, M. C. Sabel, S. Koeppen, R. Ketter, M. Weiler, G. Tabatabai, A. von Deimling, D. Gramatzki, M. Westphal, G. Schackert, M. Loeffler, M. Simon, G. Reifenberger, M. Weller
    (2013)
    Prognostic or predictive value of MGMT promoter methylation in gliomas depends on IDH1 mutation
    Neurology., Vol. 81 (17), 1515-1522
    (Impactfactor: 8,249)
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  • S. Zeynalova, M. Ziepert, M. Scholz, S. Schirm, C. Zwick, M. Pfreundschuh, M. Loeffler
    (2013)
    Comparison and modelling of pegylated or unpegylated G-CSF schedules in CHOP-14 regimen of elderly patients with aggressive B-cell lymphoma.
    Ann. Hematol., Vol. 92 (12), 1641-1652
    (Impactfactor: 2,866)
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  • David Adams, Lucia Altucci, Stylianos E Antonarakis, Juan Ballesteros, Stephan Beck, Adrian Bird, Christoph Bock, Bernhard Boehm, Elias Campo, Andrea Caricasole, Fredrik Dahl, Emmanouil T Dermitzakis, Tariq Enver, Manel Esteller, Xavier Estivill, Anne Ferguson-Smith, Jude Fitzgibbon, Paul Flicek, Claudia Giehl, Thomas Graf, Frank Grosveld, Roderic Guigo, Ivo Gut, Kristian Helin, Jonas Jarvius, Ralf Küppers, Hans Lehrach, Thomas Lengauer, ke Lernmark, David Leslie, Markus Loeffler, Elizabeth Macintyre, Antonello Mai, Joost HA Martens, Saverio Minucci, Willem H Ouwehand, Pier Giuseppe Pelicci, H léne Pendeville, Bo Porse, Vardhman Rakyan, Wolf Reik, Martin Schrappe, Dirk Schübeler, Martin Seifert, Reiner Siebert, David Simmons, Nicole Soranzo, Salvatore Spicuglia, Michael Stratton, Hendrik G Stunnenberg, Amos Tanay, David Torrents, Alfonso Valencia, Edo Vellenga, Martin Vingron, Jörn Walter, Spike Willcocks
    (2012)
    BLUEPRINT to decode the epigenetic signature written in blood.
    Nat Biotechnol., Vol. 30 (3), 224-226
    (Impactfactor: 23,268)
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  • Christiane E. Angermann, Stefan Störk, Götz Gelbrich, Hermann Faller, Roland Jahns, Stefan Frantz, Markus Loeffler, Georg Ertl
    (2012)
    Mode of Action and Effects of Standardized Collaborative Disease Management on Mortality and Morbidity in Patients with Systolic Heart Failure: The Interdisciplinary Network for Heart Failure (INH) Study
    Circulation Heart Failure, Vol. 5 (1), 25-35
    (Impactfactor: 6,286)
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  • Frank Beutner, Andrej Teren, Stephan Gielen, Gerhard Schuler, Kerstin Wirkner, Daniel Tiller, Markus Loeffler, Markus Scholz
    (2012)
    Automated photoplethysmography-based determination of ankle-brachial index: a validation study against Doppler sonography.
    Clin Res Cardiol., Vol. 101 (11), 875-883
    (Impactfactor: 2,961)
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  • Frank M. Brunkhorst, Michael Oppert, Gernot Marx, Frank Bloos, Katrin Ludewig, Christian Putensen, Axel Nierhaus, Ulrich Jaschinski, Andreas Meier-Hellmann, Andreas Weyland, Matthias Gründling, Onnen Moerer, Reimer Riessen, Armin Seibel, Maximilian Ragaller, Markus W. Büchler, Stefan John, Friedhelm Bach, Claudia Spies, Lorenz Reill, Harald Fritz, Michael Kiehntopf, Evelyn Kuhnt, Holger Bogatsch, Christoph Engel, Markus Loeffler, Marin H. Kollef, Konrad Reinhart, Tobias Welte
    (2012)
    Effect of empirical treatment with moxifloxacin and meropenem vs meropenem on sepsis-related organ dysfunction in patients with severe sepsis: a randomized trial.
    JAMA: the journal of the American Medical Association, Vol. 307 (22), 2390-2399
    (Impactfactor: 30,026)
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  • Peter Buske, Jens Przybilla, Markus Loeffler, Norman Sachs, Toshiro Sato, Hans Clevers, Joerg Galle
    (2012)
    On the biomechanics of stem cell niche formation in the gut - modelling growing organoids
    FEBS Journal, Vol. 279 (18), 3475-3487
    (Impactfactor: 3,79)
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  • Christoph Engel, Markus Loeffler, Verena Steinke, Nils Rahner, Elke Holinski-Feder, Wolfgang Dietmaier, Hans K. Schackert, Heike Goergens, Magnus von Knebel Doeberitz, Timm O. Goecke, Wolff Schmiegel, Reinhard Buettner, Gabriela Moeslein, Tom G.W. Letteboer, Encarna Go mez García, Frederik J. Hes, Nicoline Hoogerbrugge, Fred H. Menko, Theo A.M. van Os, Rolf H. Sijmons, Anja Wagner, Irma Kluijt, Peter Propping, Hans F.A. Vasen
    (2012)
    Risks of Less Common Cancers in Proven Mutation Carriers With Lynch Syndrome
    Journal of Clinical Oncology, Vol. 30 (35), 4409-4415
    (Impactfactor: 18,372)
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  • Götz Gelbrich, Frank Edelmann, Simone Inkrot, Mitja Lainscak, Svetlana Apostolovic, Aleksandar N. Neskovic, Finn Waagstein, Markus Loeffler, Stefan D. Anker, Rainer Dietz, Hans-Dirk Düngen
    (2012)
    Is target dose the treatment target? Uptitrating beta-blockers for heart failure in the elderly
    Int J Cardiol., Vol. 155 (1), 160-166
    (Impactfactor: 7,078)
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  • Christiane Heemann, Markus Kreuz, Irene Stoller, Nils Schoof, Frederike von Bonin, Marita Ziepert, Markus Löffler, Wolfram Jung, Michael Pfreundschuh, Lorenz Trümper, Dieter Kube
    (2012)
    Circulating levels of TNF- receptor II are prognostic for patients with peripheral T-cell Non-Hodgkin lymphoma
    Clin. Cancer Res., Vol. 18 (13), 3637-3647
    (Impactfactor: 7,742)
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  • Wolfram Klapper, Markus Kreuz, Christian W Kohler, Birgit Burkhardt, Monika Szczepanowski, Itziar Salaverria, Michael Hummel, Markus Loeffler, Shoji Pellissery, Wilhelm Woessmann, Carsten Schwänen, Lorenz Trümper, Swen Wessendorf, Rainer Spang, Dirk Hasenclever, Reiner Siebert
    (2012)
    Patient age at diagnosis is associated with the molecular characteristics of diffuse large B-cell lymphoma
    Blood., Vol. 119 (8), 1882-1887
    (Impactfactor: 9,898)
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  • Markus Loeffler, Lars Greulich, Patrick Scheibe, Philip Kahl, Zaki Shaikhibrahim, Ulf-Dietrich Braumann, Jens-Peer Kuska, Nicolas Wernert
    (2012)
    Classifying prostate cancer malignancy by quantitative histomorphometry.
    J Urol., Vol. 187 (5), 1867-1875
    (Impactfactor: 3,746)
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  • the ICGC MMML-Seq Project, J. Richter, M. Schlesner, S. Hoffmann, M. Kreuz, E. Leich, B. Burkhardt, M. Rosolowski, O. Ammerpohl, R. Wagener, SH. Bernhart, D. Lenze, M. Szczepanowski, M. Paulsen, S. Lipinski, RB. Russell, S. Adam-Klages, G. Apic, A. Claviez, D. Hasenclever, V. Hovestadt, N. Hornig, JO. Korbel, D. Kube, D. Langenberger, C. Lawerenz, J. Lisfeld, K. Meyer, S. Picelli, J. Pischimarov, B. Radlwimmer, T. Rausch, M. Rohde, M. Schilhabel, R. Scholtysik, R. Spang, H. Trautmann, T. Zenz, A. Borkhardt, HG. Drexler, P. Möller, RA. Macleod, C. Pott, S. Schreiber, L. Trümper, M. Loeffler, PF. Stadler, P. Lichter, R. Eils, R. Kuppers, M. Hummel, W. Klapper, P. Rosenstiel, A. Rosenwald, B. Brors, R. Siebert
    (2012)
    Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing
    Nat Genet., Vol. 44 (12), 1316-1320
    (Impactfactor: 35,532)
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  • Guido Reifenberger, Bettina Hentschel, Jörg Felsberg, Gabriele Schackert, Matthias Simon, Oliver Schnell, Manfred Westphal, Wolfgang Wick, Torsten Pietsch, Markus Löffler, Michael Weller
    (2012)
    Predictive impact of MGMT promoter methylation in glioblastoma of the elderly
    Int J Cancer., Vol. 131 (6), 1342-1350
    (Impactfactor: 5,444)
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  • N. Schmitz, S. Zeynalova, B. Glass, U. Kaiser, E. Cavallin-Stahl, M. Wolf, M. Haenel, M. Loeffler, L. Truemper, M. Pfreundschuh
    (2012)
    CNS disease in younger patients with aggressive B-cell lymphoma: an analysis of patients treated on the Mabthera International Trial and trials of the German High-Grade Non-Hodgkin Lymphoma Study Group
    Ann Oncol. , Vol. 23 (5), 1267-1273
    (Impactfactor: 6,425)
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  • Norbert Schmitz, Maike Nickelsen, Marita Ziepert, Mathias Haenel, Peter Borchmann, Christian Schmidt, Andreas Viardot, Martin Bentz, Norma Peter, Gerhard Ehninger, Gottfried Doelken, Christian Ruebe, Lorenz Truemper, Andreas Rosenwald, Michael Pfreundschuh, Markus Loeffler, Bertram Glass
    (2012)
    Conventional chemotherapy (CHOEP-14) with rituximab or high-dose chemotherapy (MegaCHOEP) with rituximab for young, high-risk patients with aggressive B-cell lymphoma: an open-label, randomised, phase 3 trial (DSHNHL 2002-1).
    Lancet Oncol, Vol. 13 (12), 1250-1259
    (Impactfactor: 22,589)
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  • René Scholtysik, Inga Nagel, Markus Kreuz, Inga Vater, Maciej Giefing, Carsten Schwaenen, Swen Wessendorf, Lorenz Trümper, Markus Loeffler, Reiner Siebert, Ralf Küppers
    (2012)
    Recurrent deletions of the TNFSF7 and TNFSF9 genes in 19p13.3 in diffuse large B-cell and Burkitt lymphomas.
    Int J Cancer., Vol. 131 (5), E830-835
    (Impactfactor: 5,444)
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  • Markus Scholz, Sibylle Schirm, Marcus Wetzler, Christoph Engel, Markus Loeffler
    (2012)
    Pharmacokinetic and -dynamic modelling of G-CSF derivatives in humans
    Theor Biol Med Model. , Vol. 9 (1), 32-73
    (Impactfactor: 1,859)
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  • Peter Buske, Jörg Galle, Nick Barker, Gabriela Aust, Hans Clevers, Markus Loeffler
    (2011)
    A Comprehensive Model of the Spatio-Temporal Stem Cell and Tissue Organisation in the Intestinal Crypt
    PLoS Comput Biol, Vol. 7 (1), 1-13
    (Impactfactor: 5,515)
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  • Frank Edelmann, Götz Gelbrich, Hans-Dirk Düngen, Stefan Fröhling, Rolf Wachter, Raoul Stahrenberg, Lutz Binder, Agnieszka Töpper, Diana Jahandar Lashki, Silja Schwarz, Christoph Herrmann-Lingen, Markus Löffler, Gerd Hasenfuss, Martin Halle, Burkert Pieske
    (2011)
    Exercise Training Improves Exercise Capacity and Diastolic Function in Patients With Heart Failure With Preserved Ejection Fraction Results of the Ex-DHF (Exercise training in Diastolic Heart Failure) Pilot Study
    J Am Coll Cardiol., Vol. 58 (17), 1780-1791
    (Impactfactor: 14,293)
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  • Jörg Felsberg, Niklas Thon, Sabina Eigenbrod, Bettina Hentschel, Michael C. Sabel, Manfred Westphal, Gabriele Schackert, Friedrich Wilhelm Kreth, Torsten Pietsch, Markus Löffler, Michael Weller, Guido Reifenberger, Jörg C. Tonn
    (2011)
    Promoter methylation and expression of MGMT and the DNA mismatch repair genes MLH1, MSH2, MSH6 and PMS2 in paired primary and recurrent glioblastomas
    Int J Cancer., Vol. 129 (3), 659-670
    (Impactfactor: 4,926)
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  • Bianca Gelbrich, Till Neumann, Stefan Esser, Anja Potthoff, Nico Reinsch, Martin Hower, Karl-Heinz Dannhauer, Markus Loeffler, Norbert H. Brockmeyer, Raimund Erbel, Götz Gelbrich
    (2011)
    Oral health and the heart - Does HIV infection open a pathophysiological gateway?
    Int J Cardiol., Vol. 151 (2), 254-257
    (Impactfactor: 6,802)
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  • Arnd Gross, Anke Tönjes, Peter Kovacs, Krishna R Veeramah, Peter Ahnert, Nab R Roshyara, Christian Gieger, Ina-Maria Rueckert, Markus Loeffler, Mark Stoneking, Heinz-Erich Wichmann, John Novembre, Michael Stumvoll, Markus Scholz
    (2011)
    Population-genetic comparison of the Sorbian isolate population in Germany with the German KORA population using genome-wide SNP arrays
    BMC Genetics, Vol. 12 (1), 67-79
    (Impactfactor: 2,489)
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  • Christian Hartmann, Bettina Hentschel, Marcos Tatagiba, Johannes Schramm, Oliver Schnell, Clemens Seidel, Robert Stein, Guido Reifenberger, Torsten Pietsch, Andreas von Deimling, Markus Löffler, Michael Weller
    (2011)
    Molecular Markers in Low-Grade Gliomas: Predictive or Prognostic?
    Clin Cancer Res., Vol. 17 (13), 4588-4599
    (Impactfactor: 7,338)
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  • Martin Hoffmann, Jens-Peer Kuska, Matthias Zscharnack, Markus Loeffler, Joerg Galle
    (2011)
    Spatial Organization of Mesenchymal Stem Cells InVitro-Results from a New Individual Cell-Based Model with Podia
    PLoS ONE, Vol. 6 (7), e21960
    (Impactfactor: 4,411)
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  • Stefanie Huhn, Dierk Ingelfinger, Justo Lorenzo Bermejo, Melanie Bevier, Barbara Pardini, Alessio Naccarati, Verena Steinke, Nils Rahner, Elke Holinski-Feder, Monika Morak, Hans K. Schackert, Heike Görgens, Christian P Pox, Timm Goecke, Matthias Kloor, Markus Loeffler, Reinhard Büttner, Ludmila Vodickova, Jan Novotny, Kubilay Demir, Cristina-Maria Cruciat, Rebecca Renneberg, Wolfgang Huber, Christof Niehrs, Michael Boutros, Peter Propping, Pavel Vodika, Kari Hemminki, Asta Försti
    (2011)
    Polymorphisms in CTNNBL1 in relation to colorectal cancer with evolutionary implications
    Int J Mol Epidemiol Genet., Vol. 2 (1), 36-50
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  • M. Pfreundschuh, E. Kuhnt, L. Trümper, A. Österborg, M. Trneny, L. Shepherd, DS. Gill, J. Walewski, R. Pettengell, U. Jaeger, PL. Zinzani, O. Shpilberg, S. Kvaloy, P. de Nully Brown, R. Stahel, N. Milpied, A. López-Guillermo, V. Poeschel, S. Grass, M. Loeffler, N. Murawski
    (2011)
    CHOP-like chemotherapy with or without rituximab in young patients with good-prognosis diffuse large-B-cell lymphoma: 6-year results of an open-label randomised study of the MabThera International Trial (MInT) Group
    Lancet Oncol., Vol. 12 (11), 1013-1022
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  • M. Rieger, A. Österborg, R. Pettengell, D. White, D. Gill, J. Walewski, E. Kuhnt, M. Loeffler, M. Pfreundschuh, A. D. Ho
    (2011)
    Primary mediastinal B-cell lymphoma treated with CHOP-like chemotherapy with or without rituximab: results of the Mabthera International Trial Group study
    Annals of Oncology, Vol. 22(3), 664-670
    (Impactfactor: 5,647)
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  • Ingo Roeder, Markus Loeffler, Ingmar Glauche, other participants
    (2011)
    Towards a quantitative understanding of stem cell-niche interaction: experiments, models, and technologies.
    Blood Cells Mol Dis., Vol. 46 (4), 308-317
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  • Itziar Salaverria, Claudia Philipp, Ilske Oschlies, Christian W Kohler, Markus Kreuz, Monika Szczepanowski, Birgit Burkhardt, Heiko Trautmann, Stefan Gesk, Miroslaw Andrusiewicz, Hilmar Berger, Miriam Fey, Lana Harder, Dirk Hasenclever, Michael Hummel, Markus Loeffler, Friederike Mahn, Idoia Martin-Guerrero, Shoji Pellissery, Christiane Pott, Michael Pfreundschuh, Alfred Reiter, Julia Richter, Maciej Rosolowski, Carsten Schwaenen, Harald Stein, Lorenz Trümper, Swen Wessendorf, Rainer Spang, Ralf Küppers, Wolfram Klapper, Reiner Siebert
    (2011)
    Translocations activating IRF4 identify a subtype of germinal-center-derived B-cell lymphoma affecting predominantly children and young adults.
    Blood., Vol. 118 (1), 139-147
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  • M. Scholz, A. Engert, J. Franklin, A. Josting, V. Diehl, D. Hasenclever, M. Loeffler
    (2011)
    Impact of first- and second-line treatment for Hodgkin's lymphoma on the incidence of AML/MDS and NHL--experience of the German Hodgkin's Lymphoma Study Group analyzed by a parametric model of carcinogenesis
    Ann Oncol., Vol. 22 (3), 681-688
    (Impactfactor: 5,647)
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  • Stephan Waldmüller, Jeanette Erdmann, Priska Binner, Götz Gelbrich, Sabine Pankuweit, Christian Geier, Bernd Timmermann, Janine Haremza, Andreas Perrot, Steffen Scheer, Rolf Wachter, Norbert Schulze-Waltrup, Anastassia Dermintzoglou, Jost Schönberger, Wolfgang Zeh, Beate Jurmann, Turgut Brodherr, Jan Börgel, Martin Farr, Hendrik Milting, Wulf Blankenfeldt, Richard Reinhardt, Cemil Özcelik, Karl-Josef Osterziel, Markus Loeffler, Bernhard Maisch, Vera Regitz-Zagrosek, Heribert Schunkert, Thomas Scheffold
    (2011)
    Novel correlations between the genotype and the phenotype of hypertrophic and dilated cardiomyopathy: results from the German Competence Network Heart Failure
    Eur J Heart Fail., Vol. 13 (11), 1185-1192
    PDF Download (207 kB, Englisch, 8 Seiten) BibTeX-Ausgabe
  • Henry Wirth, Markus Loeffler, Martin von Bergen, Hans Binder
    (2011)
    Expression cartography of human tissues using self organizing maps
    BMC Bioinformatics, Vol. 12 (1), 306 - 345
    PDF Download (16,5 MB, Englisch, 39 Seiten) BibTeX-Ausgabe
  • C. Zwick, F. Hartmann, S. Zeynalova, V. Poeschel, C. Nickenig, M. Reiser, E. Lengfelder, N. Peter, G. Schlimok, J. Schubert, N. Schmitz, M. Loeffler, M. Pfreundschuh
    (2011)
    Randomized comparison of pegfilgrastim day 4 versus day 2 for the prevention of chemotherapy-induced leukocytopenia
    Ann Oncol., Vol. 22 (8), 1872-1877
    PDF Download (283 kB, Englisch, 6 Seiten) BibTeX-Ausgabe
  • Christoph Engel, Nils Rahner, Karsten Schulmann, Elke Holinski-Feder, Timm O. Goecke, Hans K. Schackert, Matthias Kloor, Verena Steinke, Holger Vogelsang, Gabriela Möslein, Heike Görgens, Stefan Dechant, Magnus von Knebel Doeberitz, Josef Rüschoff, Nicolaus Friedrichs, Reinhard Büttner, Markus Loeffler, Peter Propping, Wolff Schmiegel, German HNPCC Consortium
    (2010)
    Efficacy of annual colonoscopic surveillance in individuals with Hereditary Non-Polyposis Colorectal Cancer
    Clinical Gastroenterology and Hepatology, Vol. 8 (2), 174-182
    (Impactfactor: 5,642)
    PDF Download (380 kB, Englisch, 9 Seiten) BibTeX-Ausgabe
  • J. Galle, A. Bader, P. Hepp, W. Grill, B. Fuchs, J.A. Käs, A. Krinner, B. Marquaß, K. Müller, J. Schiller, R.M. Schulz, M. von Buttlar, E. von der Burg, M. Zscharnack, M. Löffler
    (2010)
    Mesenchymal Stem Cells in Cartilage Repair: State of the Art and Methods to monitor Cell Growth, Differentiation and Cartilage Regeneration
    Current Medicinal Chemistry, Vol. 17 (21), 2274-2291
    (Impactfactor: 4,708)
    PDF Download (993 kB, Englisch, 18 Seiten) BibTeX-Ausgabe
  • Götz Gelbrich, Annegret Franke, Bianca Gelbrich, Susann Blüher, Markus Löffler
    (2010)
    Gummy Bears and the Pleasure of Biostatistics Lessons
    CHANCE, Vol. 23 (1), 37-38
    PDF Download (1,5 MB, Englisch, 3 Seiten) BibTeX-Ausgabe
  • B. Glass, M. Ziepert, M. Reiser, M. Freund, L. Trümper, B. Metzner, A. Feller, M. Loeffler, M. Pfreundschuh, N. Schmitz
    (2010)
    High-dose therapy followed by autologous stem-cell transplantation with and without rituximab for primary treatment of high-risk diffuse large B-cell lymphoma
    Annals of Oncology, Vol. 21 (11), 2255-2261
    (Impactfactor: 5,647)
    PDF Download (281 kB, Englisch, 7 Seiten) BibTeX-Ausgabe
  • Jürgen Graf, Andrea Reinhold, Frank M. Brunkhorst, Max Ragaller, Konrad Reinhart, Markus Loeffler, Christoph Engel
    (2010)
    Variability of structures in German intensive care units - a representative, nationwide analysis
    Wiener klinische Wochenschrift, Vol. 122 (19-20), 572-578
    (Impactfactor: 0,955)
    PDF Download (251 kB, Englisch, 7 Seiten) BibTeX-Ausgabe
  • Christian Hartmann, Bettina Hentschel, Wolfgang Wick, David Capper, Jörg Felsberg, Matthias Simon, Manfred Westphal, Gabriele Schackert, Richard Meyermann, Torsten Pietsch, Guido Reifenberger, Michael Weller, Markus Loeffler, Andreas von Deimling
    (2010)
    Patients with IDH1 wild type anaplastic astrocytomas exhibit worse prognosis than IDH1-mutated glioblastomas, and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: implications for classification of gliomas
    Acta Neuropathol, Vol. 120 (6), 707-718
    (Impactfactor: 6,397)
    PDF Download (636 kB, Englisch, 12 Seiten) BibTeX-Ausgabe
  • O. Heese, M. Schmidt, S. Nickel, H. Berger, R. Goldbrunner, J.C. Tonn, O. Bähr, J.P. Steinbach, M. Simon, J. Schramm, D. Krex, G. Schackert, T. Reithmeier, G. Nikkah, M. Löffler, M. Weller, M. Westphal
    (2010)
    Complementary therapy use in patients with glioma : An observational study
    Neurology, Vol. 75, 2229
    PDF Download (576 kB, Englisch, 9 Seiten) BibTeX-Ausgabe
  • Marion Hoffmann, Markus A. Schirmer, Mladen V. Tzvetkov, Markus Kreuz, Marita Ziepert, Leszek Wojnowski, Dieter Kube, Michael Pfreundschuh, Lorenz Trümper, Markus Loeffler, Jürgen Brockmöller
    (2010)
    A Functional Polymorphism in the NAD(P)H Oxidase Subunit CYBA Is Related to Gene Expression, Enzyme Activity, and Outcome in Non–Hodgkin Lymphoma
    Cancer Research, Vol. 70 (6), 2328-2338
    (Impactfactor: 7,543)
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  • Axel Krinner, Martin Hoffmann, Markus Loeffler, Dirk Drasdo, Joerg Galle
    (2010)
    Individual fates of mesenchymal stem cells in vitro
    BMC Systems Biology, Vol. 4, 73
    (Impactfactor: 4,064)
    PDF Download (1,3 MB, Englisch, 9 Seiten) BibTeX-Ausgabe
  • Felix Mehrhof, Markus Löffler, Götz Gelbrich, Cemil Özcelik, Maximilian Posch, Hans-Werner Hense, Ulrich Keil, Thomas Scheffold, Heribert Schunkert, Christiane Angermann, Georg Ertl, Roland Jahns, Burkert Pieske, Rolf Wachter, Frank Edelmann, Kai C. Wollert, Bernhard Maisch, Sabine Pankuweit, Raimund Erbel, Till Neumann, Wolfgang Herzog, Hugo Katus, Thomas Müller-Tasch, Christian Zugck, Hans-Dirk Düngen, Vera Regitz-Zagrosek, Elke Lehmkuhl, Stefan Störk, Uwe Siebert, Jürgen Wasem, Anja Neumann, Alexander Göhler, Stefan D. Anker, Friedrich Köhler, Martin Möckel, Karl-Josef Osterziel, Rainer Dietz, Mathias Rauchhaus
    (2010)
    A network against failing hearts - Introducing the German Competence Network Heart Failure
    Int J Cardiol, Vol. 145(1), 135-138
    (Impactfactor: 3,469)
    PDF Download (234 kB, Englisch, 4 Seiten) BibTeX-Ausgabe
  • German Ott, Marita Ziepert, Wolfram Klapper, Heike Horn, Monika Szczepanowski, Heinz-Wolfram Bernd, Christoph Thorns, Alfred C. Feller, Dido Lenze, Michael Hummel, Harald Stein, Hans-Konrad Müller-Hermelink, Matthias Frank, Martin-Leo Hansmann, Thomas F. E. Barth, Peter Möller, Sergio Cogliatti, Michael Pfreundschuh, Norbert Schmitz, Lorenz Trümper, Markus Loeffler, Andreas Rosenwald
    (2010)
    Immunoblastic morphology but not the immunohistochemical GCB/nonGCB classifier predicts outcome in diffuse large B-cell lymphoma in the RICOVER-60 trial of the DSHNHL.
    Blood., Vol. 116 (23), 4916-4925
    (Impactfactor: 10,555)
    PDF Download (1,2 MB, Englisch, 11 Seiten) BibTeX-Ausgabe
  • M. Rieger, A. Österborg, R. Pettengell, D. White, D. Gill, J. Walewski, E. Kuhnt, M. Loeffler, M. Pfreundschuh, A. D. Ho
    (2010)
    Primary mediastinal B-cell lymphoma treated with CHOP-like chemotherapy with or without rituximab: results of the Mabthera International Trial Group study
    Annals of Oncology,
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  • Patrick Scheibe, Ulf-Dietrich Braumann, Jens-Peer Kuska, Markus Löffler, Jan C. Simon, Uwe Paasch, Tino Wetzig
    (2010)
    Image-processing chain for a three-dimensional reconstruction of basal cell carcinomas
    Experimental Dermatology, Vol. 19 (7), 689-691
    (Impactfactor: 3,239)
    PDF Download (248 kB, Englisch, 3 Seiten) BibTeX-Ausgabe
  • Patrick Scheibe, Tino Wetzig, Jens-Peer Kuska, Markus Löffler, Jan C. Simon, Uwe Paasch, Ulf-Dietrich Braumann
    (2010)
    3D-Reconstruction of Basal Cell Carcinoma
    Lecture Notes in Computer Science, 25-36
    PDF Download (4,9 MB, Englisch, 12 Seiten) BibTeX-Ausgabe
  • Norbert Schmitz, Lorenz Trümper, Marita Ziepert, Maike Nickelsen, Anthony D. Ho, Bernd Metzner, Norma Peter, Markus Loeffler, Andreas Rosenwald, Michael Pfreundschuh
    (2010)
    Treatment and prognosis of mature T-cell and NK-cell lymphoma: an analysis of patients with T-cell lymphoma treated in studies of the German High-Grade Non-Hodgkin Lymphoma Study Group.
    Blood., Vol. 116 (18), 3418-3425
    (Impactfactor: 10,555)
    PDF Download (426 kB, Englisch, 9 Seiten) BibTeX-Ausgabe
  • René Scholtysik, Markus Kreuz, Wolfram Klapper, Birgit Burkhardt, Alfred C. Feller, Michael Hummel, Markus Loeffler, Maciej Rosolowski, Carsten Schwaenen, Rainer Spang, Harald Stein, Christoph Thorns, Lorenz Trümper, Inga Vater, Swen Wessendorf, Thorsten Zenz, Reiner Siebert, Ralf Küppers
    (2010)
    Detection of genomic aberrations in molecularly defined Burkitt's lymphoma by array-based, high resolution, single nucleotide polymorphism analysis.
    Haematologica., Vol. 95 (12), 2047-2055
    (Impactfactor: 6,416)
    PDF Download (3,0 MB, Englisch, 9 Seiten) BibTeX-Ausgabe
  • M. Scholz, A. Engert, J. Franklin, A. Josting, V. Dieh, D. Hasenclever, M. Loeffler
    (2010)
    Impact of first- and second-line treatment for Hodgkin's lymphoma on the incidence of AML/MDS and NHL--experience of the German Hodgkin's Lymphoma Study Group analyzed by a parametric model of carcinogenesis.
    Annals of Oncology,
    PDF Download (233 kB, Englisch, 8 Seiten) BibTeX-Ausgabe
  • M. Scholz, A. Gross, M. Loeffler
    (2010)
    A biomathematical model of human thrombopoiesis under chemotherapy
    Journal of Theoretical Biology, Vol. 264 (2), 287-300
    (Impactfactor: 2,574)
    PDF Download (1,0 MB, Englisch, 14 Seiten) BibTeX-Ausgabe
  • S. Stäubert, A. Winter, R. Speer, M. Löffler
    (2010)
    Designing a concept for an IT-infrastructure for an integrated research and treatment center.
    Stud Health Technol Inform, 160(Pt 2), 1319-1323
    PDF Download (282 kB, Englisch, 5 Seiten) BibTeX-Ausgabe
  • C. Terschueren, S. Gierer, C. Brillant, U. Paulus, M. Loeffler, W. Hoffmann
    (2010)
    Are patients with Hodgkin lymphoma and high-grade non-Hodgkin lymphoma in clinical therapy optimization protocols representative of these groups of patients in Germany?
    Annals of Oncology, Vol. 21 (10), 2045-2051
    (Impactfactor: 5,647)
    PDF Download (88 kB, Englisch, 7 Seiten) BibTeX-Ausgabe
  • D Teupser, R Baber, U Ceglarek, M Scholz, T Illig, C Gieger, LM Holdt, A Leichtle, KH Greiser, D Huster, P Linsel-Nitschke, A Schäfer, PS Braund, L Tiret, K Stark, D Raaz-Schrauder, GM Fiedler, W Wilfert, F Beutner, S Gielen, A Grosshennig, IR König, P Lichtner, IM Heid, A Kluttig, NE El Mokhtari, D Rubin, AB Ekici, A Reis, CD Garlichs, AS Hall, G Matthes, C Wittekind, C Hengstenberg, F Cambien, S Schreiber, K Werdan, T Meitinger, M Loeffler, NJ Samani, J Erdmann, HE Wichmann, H Schunkert, J Thiery
    (2010)
    Genetic regulation of serum phytosterol levels and risk of coronary artery disease.
    Circ Cardiovasc Genet, Vol. 3 (4), 331-339
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  • Marita Ziepert, Dirk Hasenclever, Evelyn Kuhnt, Bertram Glass, Norbert Schmitz, Michael Pfreundschuh, Markus Loeffler
    (2010)
    Standard International Prognostic Index Remains a Valid Predictor of Outcome for Patients With Aggressive CD20+ B-Cell Lymphoma in the Rituximab Era
    Journal of Clinical Oncology, Vol. 28 (14), 2373-2380
    (Impactfactor: 17,793)
    PDF Download (274 kB, Englisch, 8 Seiten) BibTeX-Ausgabe
  • Heinz-Wolfram Bernd, Marita Ziepert, Christoph Thorns, Wolfram Klapper, Hans-Heinrich Wacker, Michael Hummel, Harald Stein, Martin-Leo Hansmann, German Ott, Andreas Rosenwald, Hans-Konrad Müller-Hermelink, Thomas F. E. Barth, Peter Möller, Sergio B. Cogliatti, Michael Pfreundschuh, Norbert Schmitz, Lorenz Trümper, Silvia Höller, Markus Löffler, Alfred C. Feller
    (2009)
    Loss of HLA-DR expression and immunoblastic morphology predict adverse outcome in diffuse large B-cell lymphoma – analyses of cases from two prospective randomized clinical trials
    haematologica , 94 (11) , 1569 - 1580
    PDF Download (290 kB, Englisch, 12 Seiten) BibTeX-Ausgabe
  • Volkmar Boehme, Norbert Schmitz, Samira Zeynalova, Markus Loeffler, Michael Pfreundschuh
    (2009)
    CNS events in elderly patients with aggressive lymphoma treated with modern chemotherapy (CHOP-14) with or without rituximab: an analysis of patients treated in the RICOVER-60 trial of the German High-Grade Non-Hodgkin Lymphoma Study Group (DSHNHL).
    Blood, 113 (17), 3896 - 3902
    PDF Download (427 kB, Englisch, 8 Seiten) BibTeX-Ausgabe
  • Andreas Engert, Volker Diehl, Jeremy Franklin, Andreas Lohri, Bernd Dörken, Wolf-Dieter Ludwig, Peter Koch, Mathias Hänel, Michael Pfreundschuh, Martin Wilhelm, Lorenz Trümper, Walter-Erich Aulitzky, Martin Bentz, Mathias Rummel, Orhan Sezer, Hans-Konrad Müller-Hermelink, Dirk Hasenclever, Markus Löffler
    (2009)
    Escalated-Dose BEACOPP in the Treatment of Patients With Advanced-Stage Hodgkin's Lymphoma: 10 Years of Follow-Up of the GHSG HD9 Study
    Journal of Clinical Oncology , Vol. 27 (27), 4548 - 4554
    PDF Download (189 kB, Englisch, 7 Seiten) BibTeX-Ausgabe
  • Ingmar Glauche, Kateri Moore, Lars Thielecke, Katrin Horn, Markus Loeffler, Ingo Roeder
    (2009)
    Stem Cell Proliferation and Quiescence—Two Sides of the Same Coin
    PLoS Computational Biology, 5 (7), 1-10
    PDF Download (393 kB, Englisch, 10 Seiten) BibTeX-Ausgabe
  • Monika K. Graeser, Christoph Engel, Kerstin Rhiem, Dorothea Gadzicki, Ulrich Bick, Karin Kast, Ursula G. Froster, Bettina Schlehe, Astrid Bechthold, Norbert Arnold, Sabine Preisler-Adams, Carolin Nestle-Kraemling, Mohammad Zaino, Markus Loeffler, Marion Kiechle, Alfons Meindl, Dominic Varga, Rita K. Schmutzler
    (2009)
    Contralateral Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers
    Journal of Clinical Oncology, Vol. 27 Nr. 35, 5887-5892
    PDF Download (390 kB, Englisch, 6 Seiten) BibTeX-Ausgabe
  • Scholz M, Ackermann M, Engel C, Emmrich F, Loeffler M, Kamprad M.
    (2009)
    A pharmacokinetic model of filgrastim and pegfilgrastim application in normal mice and those with cyclophosphamide-induced granulocytopaenia
    Cell Proliferation , 42, 813-822
    PDF Download (679 kB, Englisch, 10 Seiten) BibTeX-Ausgabe
  • Monica Marra, Daniele Santini, Giuseppina Meo, Bruno Vincenzi, Silvia Zappavigna, Alfonso Baldi, Maciej Rosolowski, Giuseppe Tonini, Markus Loeffler, Ruth Lupu, Santolo Rosario Addeo, Alberto Abbruzzese, Alfredo Budillon, Michele Caraglia
    (2009)
    Cyr61 downmodulation potentiates the anticancer effects of zoledronic acid in androgen-independent prostate cancer cells
    International Journal of Cancer, 125, 2004 - 2013
    PDF Download (477 kB, Englisch, 10 Seiten) BibTeX-Ausgabe
  • J. I. Martin-Subero, M. Kreuz, M. Bibikova, S. Bentink, O. Ammerpohl, E. Wickham-Garcia, M. Rosolowski, J. Richter, L. Lopez-Serra, E. Ballestar, H. Berger, X. Agirre, H. W. Bernd, V. Calvanese, S. B. Cogliatti, H. G. Drexler, J. B. Fan, M. F. Fraga, M. L. Hansmann, M. Hummel, W. Klapper, B. Korn, R. Kuppers, R.A. Macleod, P. Möller, G. Ott, C. Pott, F. Prosper, A. Rosenwald, C. Schwaenen, D. Schubeler, M Seifert, B. Sturzenhofecker, M. Weber, S. Wessendorf, M. Loeffler, L. Truemper, H. Stein, R. Spang, M. Esteller, D. Barker, D. Hasenclever, R. Siebert
    (2009)
    New insights into the biology and origin of mature aggressive B-cell lymphomas by combined epigenomic, genomic and transcriptional profiling.
    Blood, 113 (11), 2488 - 2497
    PDF Download (1,5 MB, Englisch, 11 Seiten) BibTeX-Ausgabe
  • C.S. Potten, R. Gandara, Y.R. Mahida, M. Loeffler, N.A. Wright
    (2009)
    The stem cells of small intestinal crypts: where are they?
    Cell Proliferation , 42(6), 731-750
    PDF Download (718 kB, Englisch, 20 Seiten) BibTeX-Ausgabe
  • Norbert Schmitz, Samira Zeynalova, Markus Loeffler, Michael Pfreundschuh
    (2009)
    Response:Intrathecal methotrexate and central nervous system events
    BLOOD , 114(9), 1999 - 2000
    PDF Download (158 kB, Englisch, 3 Seiten) BibTeX-Ausgabe
  • Markus Scholz, Manuela Ackermann, Frank Emmrich, Markus Loeffler, Manja Kamprad
    (2009)
    Effectiveness of cytopenia prophylaxis for different filgrastim and pegfilgrastim schedules in a chemotherapy mouse model
    Biologics: Targets & Therapy, 3, 27 - 37
    PDF Download (845 kB, Englisch, 11 Seiten) BibTeX-Ausgabe
  • Markus Scholz, Christoph Engel, D Apt, SL Sankar, E Goldstein, Markus Löffler
    (2009)
    Pharmacokinetic and pharmacodynamic modelling of the novel human granulocyte colony-stimulating factor derivative Maxy-G34 and pegfilgrastim in rats
    Cell Proliferation , 42, 823-837
    PDF Download (922 kB, Englisch, 15 Seiten) BibTeX-Ausgabe
  • N. Schoof, F. von Bonin, Samira Zeynalova, Marita Ziepert, W. Jung, Markus Loeffler, M. Pfreundschuh, L. Truemper, D. Kube
    (2009)
    Favorable impact of the Interleukin-4 receptor allelic variant I75 on the survival of diffuse large B-cell lymphoma patients demonstrated in a large prospective clinical trial
    Annals of Oncology , 20, 1548 - 1554
    PDF Download (305 kB, Englisch, 7 Seiten) BibTeX-Ausgabe
  • Carsten Schwaenen, Andreas Viardot, Hilmar Berger, Thomas F. E. Barth, Stefan Bentink, Hartmut Döhner, Martina Enz, Alfred C. Feller, Martin-Leo Hansmann, Michael Hummel, Hans A. Kestler, Wolfram Klapper, Markus Kreuz, Dido Lenze, Markus Loeffler, Peter Möller, Hans-Konrad Müller-Hermelink, German Ott, Maciej Rosolowski, Andreas Rosenwald, Sandra Ruf, Reiner Siebert, Rainer Spang, Harald Stein, Lorenz Truemper, Peter Lichter, Martin Bentz, Swen Wessendorf, Molecular Mechanisms in Malignant Lymphomas Network
    (2009)
    Microarray-Based Genomic Profiling Reveals Novel Genomic Aberrations in Follicular Lymphoma Which Associate with Patient Survival and Gene Expression Status
    Genes, Chromosomes & Cancer, 48 (1), 39 - 54
    PDF Download (461 kB, Englisch, 16 Seiten) BibTeX-Ausgabe
  • Michael Weller, Jörg Felsberg, Christian Hartmann, Hilmar Berger, Joachim P. Steinbach, Johannes Schramm, Manfred Westphal, Gabriele Schackert, Matthias Simon, Jörg C. Tonn, Oliver Heese, Dietmar Krex, Guido Nikkhah, Torsten Pietsch, Otmar Wiestler, Guido Reifenberger, Andreas von Deimling, Markus Loeffler
    (2009)
    Molecular Predictors of Progression-Free and Overall Survival in Patients With Newly Diagnosed Glioblastoma: A Prospective Translational Study of the German Glioma Network
    Journal of Clinical Oncology , Vol. 27 Nr. 34, 5743-5750
    PDF Download (454 kB, Englisch, 8 Seiten) BibTeX-Ausgabe
  • S. Bentink, S. Wessendorf, C. Schwaenen, M. Rosolowski, W. Klapper, A. Rosenwald, G. Ott, A. H. Banham, H. Berger, A. C. Feller, M.-L. Hansmann, D. Hasenclever, M. Hummel, D. Lenze, P. Möller, B. Stuerzenhofecker, M. Loeffler, L. Truemper, H. Stein, R. Siebert, R. Spang, for the Molecular Mechanism in Malignant Lymphomas Network, Project of the Deutsche Krebshilfe
    (2008)
    Pathway activation patterns in diffuse large B-cell lymphomas
    Leukemia, 22, 1746-1754
    (Impactfactor: 6,924)
    PDF Download (931 kB, Englisch, 9 Seiten) BibTeX-Ausgabe
  • Frank M. Brunkhorst, Christoph Engel, Frank Bloos, Andreas Meier-Hellmann, Max Ragaller, Norbert Weiler, Onnen Moerer, Matthias Gruendling, Michael Oppert, Stefan Grond, Derk Olthoff, Ulrich Jaschinski, Stefan John, Rolf Rossaint, Tobias Welte, Martin Schaefer, Peter Kern, Evelyn Kuhnt, Michael Kiehntopf, Christiane Hartog, Charles Natanson, Markus Loeffler, Konrad Reinhart, for the German Competence Network Sepsis (SepNet)
    (2008)
    Intensive Insulin Therapy and Petastarch Resuscitation in Severe Sepsis
    The New England Journal of Medicine, 358, 125-139
    (Impactfactor: 52,589)
    PDF Download (366 kB, Englisch, 15 Seiten) BibTeX-Ausgabe
  • Frank M. Brunkhorst, Christoph Engel, Max Ragaller, Tobias Welte, Rolf Rossaint, Herwig Gerlach, Konstantin Mayer, Stefan John, Frank Stuber, Norbert Weiler, Michael Oppert, Onnen Moerer, Holger Bogatsch, Konrad Reinhart, Markus Loeffler, Christiane Hartog, for the German Competence Network Sepsis (SepNet)
    (2008)
    Practice an perception - A nationwide survey of therapy habits in sepsis
    Critical Care Medicine, 36(10), 2719-2725
    (Impactfactor: 6,283)
    PDF Download (400 kB, Englisch, 7 Seiten) BibTeX-Ausgabe
  • Judith Dierlamm, Eva M. Murga Penas, Stefan Bentink, Swen Wessendorf, Hilmar Berger, Michael Hummel, Wolfram Klapper, Dido Lenze, Andreas Rosenwald, Eugenia Haralambieva, German Ott, Sergio B. Cogliatti, Peter Möller, Carsten Schwaenen, Harald Stein, Markus Löffler, Rainer Spang, Lorenz Trümper, Reiner Siebert, for the Deutsche Krebshilfe Network Project, "Molecular Mechanisms in Malignant Lymphomas"
    (2008)
    Gain of chromosome region 18q21 including the MALT1 gene is associated with the activated B-cell-like gene expression subtype and increased BCL2 gene dosage and protein expression in diffuse large B-cell lymphoma
    Haematologica, 93(5), 688-696
    (Impactfactor: 5,516)
    PDF Download (180 kB, Englisch, 9 Seiten) BibTeX-Ausgabe
  • Gunnar Elke, Dirk Schädler, Christoph Engel, Holger Bogatsch, Inez Frerichs, Maximilian Ragaller, Jens Scholz, Frank M. Brunkhorst, Markus Löffler, Konrad Reinhart, Norbert Weiler, for the German Competence Network Sepsis (SepNet)
    (2008)
    Current practice in nutritional support and its association with mortality in septic patients -- Results from a national, prospective, multicenter study
    Critical Care Medicine, 36(6), 1762-1767
    (Impactfactor: 6,283)
    PDF Download (136 kB, Englisch, 6 Seiten) BibTeX-Ausgabe
  • Bernd Frank, Barbara Burwinkel, Justo Lorenzo Bermejo, Asta Försti, Kari Hemminiki, Richard Houlston, Elisabeth Mangold, Nils Rahner, Waltraud Friedl, Nicolaus Friedrichs, Reinhard Buettner, Christoph Engel, Markus Loeffler, Elke Holinski-Feder, Monika Morak, Gisela Keller, Hans K. Schackert, Stefan Krüger, Timm Goecke, Gabriela Moeslein, Matthias Kloor, Johannes Gebert, Erdmute Kunstmann, Karsten Schulmann, Josef Rüschoff, Peter Propping, The German HNPCC Consortium
    (2008)
    Ten recently identified associations between nsSNPs and colorectal cancer could not be replicated in German families
    Cancer Letters, 271, 153-157
    (Impactfactor: 2,398)
    PDF Download (100 kB, Englisch, 5 Seiten) BibTeX-Ausgabe
  • Martin Hoffmann, Hannah H. Chang, Sui Huang, Donald E. Ingber, Markus Loeffler, Joerg Galle
    (2008)
    Noise-Driven Stem Cell and Progenitor Population Dynamics
    PLOS one, 3(8), e2922
    PDF Download (357 kB, Englisch, 10 Seiten) BibTeX-Ausgabe
  • Matthias Horn, Markus Loeffler, Ingo Roeder
    (2008)
    Mathematical Modeling of Genesis and Treatment of Chronic Myeloid Leukemia
    Cells Tissues Organs, 188, 236-247
    (Impactfactor: 1,776)
    PDF Download (420 kB, Englisch, 12 Seiten) BibTeX-Ausgabe
  • W. Klapper, H. Stoecklein, S. Zeynalova, G. Ott, F. Kosari, A. Rosenwald, M. Loeffler, L. Trümper, M. Pfreundschuh, R. Siebert
    (2008)
    Structural aberrations affecting the MYC locus indicate a poor prognosis independent of clinical risk factors in diffuse large B-cell lymphomas treated ithin randomized trials of the German High-Grade Non-Hodgkin's Lymphoma Study Group (DSHNHL)
    Leukemia, 22, 2226-2229
    (Impactfactor: 6,924)
    BibTeX-Ausgabe
  • Wolfram Klapper, Monika Szczepanowski, Birgit Burkhardt, Berger Hilmar, Maciej Rosolowski, Stefan Bentink, Carsten Schwaenen, Swen Wessendorf, Rainer Spang, Peter Möller, Martin Leo Hansmann, Heinz-Wolfram Bernd, German Ott, Michael Hummel, Harald Stein, Markus Loeffler, Lorenz Trümper, Martin Zimmermann, Alfred Reiter, Reiner Siebert, for the "Molecular Mechanisms in Malignant Lymphomas" Network, Project of the Deutsche Krebshilfe
    (2008)
    Molecular profiling of pediatric mature B-cell lymphoma treated in population-based prospective clinical trials
    Blood, 112, 1374-1381
    (Impactfactor: 10,896)
    PDF Download (614 kB, Englisch, 9 Seiten) BibTeX-Ausgabe
  • Dieter Kube, Thanh-Duc Hua, Frederike von Bonin, Nils Schoof, Samira Zeynalova, Marita Klöss, Daniela Gocht, Bernd Potthoff, Mladen Tzvetkov, Jürgen Brockmöller, Markus Löffler, Michael Pfreundschuh, Lorenz Trümper
    (2008)
    Effect of Interleukin-10 Gene Polymorphisms on Clinical Outcome of Patients with Aggressive Non-Hodgkin's Lymphoma: An Exploratory Study
    Clinical Cancer Research, 14(12), 3777-3784
    (Impactfactor: 6,25)
    PDF Download (261 kB, Englisch, 8 Seiten) BibTeX-Ausgabe
  • Michael Oppert, Christoph Engel, Frank-Martin Brunkhorst, Holger Bogatsch, Konrad Reinhart, Ulrich Frei, Kai-Uwe Eckardt, Markus Loeffler, Stefan John, for the German Competence Network Sepsis (SepNet)
    (2008)
    Acute renal failure in patients with severe sepsis and septic shock - a significant independent risk factor for mortality: results from the German Prevalence Study
    Nephrology Dialysis Transplantation, 23(3), 904-909
    (Impactfactor: 3,167)
    PDF Download (123 kB, Englisch, 6 Seiten) BibTeX-Ausgabe
  • M. Pfreundschuh, C. Zwick, S. Zeynalova, U. Dührsen, K.-H. Pflüger, T. Vrieling, R. Mesters, H.-G. Mergenthaler, H. Einsele, M. Bentz, E. Lengfelder, L. Trümper, C. Rübe, N. Schmitz, M. Loeffler, On behalf of the DSHNHL
    (2008)
    Dose-escalated CHOEP for the treatment of young patients with aggressive non-Hodgkin’s lymphoma: II. Results of the randomized high-CHOEP trial of the German High-Grade Non-Hodgkin’s Lymphoma Study Group (DSHNHL)
    Annals of Oncology, 19(3), 545-552
    (Impactfactor: 4,875)
    PDF Download (330 kB, Englisch, 8 Seiten) BibTeX-Ausgabe
  • Michael Pfreundschuh, Anthony D Ho, Eva Cavallin-Stahl, Max Wolf, Ruth Pettengell, Ingrid Vasova, Andrew Belch, Jan Walewski, Pier-Luigi Zinzani, Walter Mingrone, Stein Kvaloy, Ofer Shpilberg, Ulrich Jaeger, Mads Hansen, Claudia Corrado, Adriana Scheliga, Markus Loeffler, Evelyn Kuhnt, for the MabThera International Trial (MinT) Group
    (2008)
    Prognostic significance of maximum tumour (bulk) diameter in young patients with good-prognosis diffuse large-B-cell lymphoma treated with CHOP-like chemotherapy with or without rituximab: an exploratory analysis of the MabThera Intern. Trial Group study
    The Lancet, Oncology, 9(5), 435-444
    (Impactfactor: 12,247)
    PDF Download (269 kB, Englisch, 10 Seiten) BibTeX-Ausgabe
  • Michael Pfreundschuh, Joerg Schubert, Marita Ziepert, Rudolf Schmits, Martin Mohren, Eva Lengfelder, Marcel Reiser, Christina Nickenig, Michael Clemens, Norma Peter, Carsten Bokemeyer, Hartmut Eimermacher, Anthony Ho, Martin Hoffmann, Roland Mertelsmann, Lorenz Trümper, Leopold Balleisen, Ruediger Liersch, Bernd Metzner, Frank Hartmann, Bertram Glass, Viola Poeschel, Norbert Schmitz, Christian Ruebe, Alfred C. Feller, Markus Loeffler, for the German High-Grade Non-Hodgkin Lymphoma Study Group
    (2008)
    Six versus eight cycles of bi-weekly CHOP-14 with or without rituximab in elderly patients with aggressive CD20+B-cell lymphomas: a randomised controlled trial (RICOVER-60)
    Lancet Oncology, 9(2), 105-116
    (Impactfactor: 12,247)
    PDF Download (278 kB, Englisch, 12 Seiten) BibTeX-Ausgabe
  • K. Reinhart, F. M. Brunkhorst, C. Engel, F. Bloos, A. Meier-Hellmann, M. Ragaller, N. Weiler, O. Moerer, M. Gruendling, M. Oppert, S. Grond, D. Olthoff, U. Jaschinski, S. John, R. Rossaint, T. Welte, M. Schaefer, P. Kern, E. Kuhnt, M. Kiehntopf, T. Deufel, C. Hartog, H. Gerlach, F. Stüber, H.-D. Volk, M. Quintel, M. Loeffler, für die Deutsche Studiengruppe Kompentenznetzwerk Sepsis SepNet
    (2008)
    Studienprotokoll der VISEP-Studie; Entgegnung der SepNet-Studiengruppe
    Der Anaesthesist 2008, 57(7), 723-728
    (Impactfactor: 0,777)
    PDF Download (292 kB, 6 Seiten) BibTeX-Ausgabe
  • Ingo Roeder, Katrin Horn, Hans-Bernd Sieburg, Rebecca Cho, Christa Mueller-Sieburg, Markus Loeffler
    (2008)
    Characterization and quantification of clonal heterogeneity among hematopoietic stem cells: a model-based approach
    Blood, 112(13), 4874-4883
    (Impactfactor: 10,986)
    PDF Download (1008 kB, 11 Seiten) BibTeX-Ausgabe
  • Anja Roehle, Kai P. Hoefig, Dirk Repsilber, Christoph Thorns, Marita Ziepert, Kai O. Wesche, Marlen Thiere, Markus Loeffler, Wolfram Klapper, Michael Pfreundschuh, András Matolcsy, Heinz-Wolfram Bernd, Lila Reiniger, Hartmut Merz, Alfred C. Feller
    (2008)
    MicroRNA signatures characterize diffuse large B-cell lymphomas and follicular lymphomas
    British Journal of Haematology, 142(5), 732-744
    (Impactfactor: 4,49)
    PDF Download (628 kB, Englisch, 13 Seiten) BibTeX-Ausgabe
  • Markus Scholz, Harald Niesch, Olaf Steffen, Baerbel Ernst, Markus Loeffler, Evelin Witruk, Hans Schwarz
    (2008)
    IMPACT OF CHESS TRAINING ON MATHEMATICS PERFORMANCE AND CONCENTRATION ABILITY OF CHILDREN WITH LEARNING DISABILITIES
    INTERNATIONAL JOURNAL OF SPECIAL EDUCATION , 23(3), 138-148
    PDF Download (254 kB, Englisch, 11 Seiten) BibTeX-Ausgabe
  • L. Trümper, C. Zwick, M. Ziepert, K. Hohloch, R. Schmits, M. Mohren, R. Liersch, M. Bentz, U. Graeven, U. Wruck, M. Hoffmann, B. Metzner, D. Hasenclever, M. Loeffler, M. Pfreundschuh, On behalf of the DSHNHL
    (2008)
    Dose-escalated CHOEP for the treatment of young patients with aggressive non-Hodgkin’s lymphoma: I. A randomized dose escalation and feasibility study with bi- and tri-weekly regimens
    Annals of Oncology, 19(3), 538-544
    (Impactfactor: 4,875)
    PDF Download (170 kB, Englisch, 7 Seiten) BibTeX-Ausgabe
  • M. Ziepert, R. Schmits, L. Truemper, M. Pfreundschuh, M. Loeffler
    (2008)
    Prognostic factors for hematotoxicity of chemotherapy in aggressive non-Hodgkin’s lymphoma
    Annals of Oncology, Vol. 19 (4), 752–762
    BibTeX-Ausgabe
  • M. Ziepert, R. Schmits, L. Trümper, M. Pfreundschuh, M. Loeffler, On behalf of the DSHNHL
    (2008)
    Prognostic factors for hematotoxicity of chemotherapy in aggressive non-Hodgkin’s lymphoma
    Annals of Oncology, 19(4), 752-762
    (Impactfactor: 4,875)
    PDF Download (465 kB, Englisch, 11 Seiten) BibTeX-Ausgabe
  • V. Boehme, S. Zeynalova, M. R. Kloess, M. Loeffler, U. Kaiser, M. Pfreundschuh, N. Schmitz
    (2007)
    Incidence and risk factors of central nervous system recurrence in aggressive lymphoma - a survey of 1693 patients treated in protocols of the German High-Grade Non-Hodgkin's Lymphoma Study Group (DSHNHL)
    Annals of Oncology, 18 (1), 149-157
    (Impactfactor: 5,179)
    PDF Download (171 kB, Englisch, 9 Seiten) BibTeX-Ausgabe
  • U.-D. Braumann, N. Scherf, J. Einenkel, L.-C. Horn, N. Wentzensen, M. Loeffler, J.-P. Kuska
    (2007)
    Large Histological Serial Sections for Computational Tissue Volume Reconstruction
    Methods of Information in Medicine, 5, 614-622
    (Impactfactor: 1,684)
    PDF Download (977 kB, Englisch, 9 Seiten) BibTeX-Ausgabe
  • C. Engel, F. M. Brunkhorst, H. G. Bone, R. Brunkhorst, H. Gerlach, S. Grond, M. Gruendling, G. Huhle, U. Jaschinski, S. John, K. Mayer, M. Oppert, D. Olthoff, M. Quintel, M. Ragaller, R. Rossaint, F. Stuber, N. Weiler, T. Welte, H. Bogatsch, C. Hartog, M. Loeffler, K. Reinhart, for the Competence Network Sepsis (SepNet)
    (2007)
    Epidemiology of sepsis in Germany: Results from a national prospective multicenter study
    Intensive Care Medicine, 33(4), 606-618
    (Impactfactor: 4,406)
    PDF Download (185 kB, Englisch, 13 Seiten) BibTeX-Ausgabe
  • Andreas Engert, Jeremy Franklin, Hans Theodor Eich, Corinne Brillant, Susanne Sehlen, Claudio Cartoni, Richard Herrmann, Michael Pfreundschuh, Markus Sieber, Hans Tesch, Astrid Franke, Peter Koch, Maike de Wit, Ursula Paulus, Dirk Hasenclever, Markus Loeffler, Rolf-Peter Müller, Hans Konrad Müller-Hermelink, Eckhart Dühmke, Volker Diehl
    (2007)
    Two Cycles of Doxorubicin, Bleomycin, Vinblastine, and Dacarbazine Plus Extended-Field Radiotherapy is Superior to Radiotherapy Alone in Early Favorable Hodgkin's Lymphoma: Final Results of the GHSG HD7 Trial
    Journal of Clinical Oncology, 25(23), 3495-3502
    (Impactfactor: 13,598)
    PDF Download (188 kB, Englisch) BibTeX-Ausgabe
  • I. Glauche, M. Cross, M. Loeffler, I. Roeder
    (2007)
    Lineage Specification of Hematopoietic Stem Cells: Mathematical Modeling and Biological Implication
    Stem Cells (Dayt), 25, 1791-1799
    (Impactfactor: 7,924)
    PDF Download (814 kB, Englisch) BibTeX-Ausgabe
  • M. Kreuz, M. Rosolowski, H. Berger, C. Schwaenen, S. Wessendorf, M. Loeffler, D. Hasenclever
    (2007)
    Develment and Implementation of an Analysis Tool for Array-based Comparative Genomic Hybridization
    Methods of Information in Medicine, 5, 608-613
    (Impactfactor: 1,684)
    PDF Download (421 kB, Englisch, 6 Seiten) BibTeX-Ausgabe
  • D. Kube, T.-D. Hua, M. Klöss, B. Kulle, J. Brockmöller, L. Wojnowski, M. Löffler, M. Pfreundschuh, L. Trümper
    (2007)
    The Interleukin-10 gene promoter polymorphism-1087AG does not correlate with clinical outcome in Non-Hodgkin lymphoma
    Genes and Immunity, 8(2), 164-167
    (Impactfactor: 4,533)
    PDF Download (103 kB, Englisch) BibTeX-Ausgabe
  • T. Neumann, S. Esser, A. Potthoff, S. Pankuweit, A. Neumann, F. Breuckmann, K. Neuhaus, J. Kondratieva, T. Buck, T. Müller-Tasch, R. Wachter, C. Prettin, G. Gelbrich, W. Herzog, B. Pieske, M. Rauchhaus, M. Löffler, B. Maisch, A. Mügge, J. Wasem, G. Gerken, N. H. Brockmeyer, R. Erbel, for the HIV-HEART Study Investigative Group
    (2007)
    Prevalence and Natural History of Heart Failure in Outpatient HIV-infected Subjects: Rationale and Design of the HIV-Heart Study
    European Journal of Medical Research, 12, 243-248
    (Impactfactor: 1,046)
    PDF Download (766 kB, Englisch) BibTeX-Ausgabe
  • Ingo Roeder, Katrin Braesel, Ronny Lorenz, Markus Loeffler
    (2007)
    Stem cell fate analysis revisited: Interpretation of individual clone dynamics in the light of a new paradigm of stem cell organization
    Journal of Biomedicine and Biotechnology, 2007/84656, 1-9
    (Impactfactor: 1,829)
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  • M. Weller, H. Berger, C. Hartmann, J. Schramm, M. Westphal, M. Simon, R. Goldbrunner, D. Krex, J. P. Steinbach, C. B. Ostertag, M. Loeffler, T. Pietsch, A. von Deimling, German Glioma Network
    (2007)
    Combined 1p/19q loss in oligodendroglial tumors: predicitve or prognostic biomarker?
    Clinical Cancer Research, 13(23), 6933-6937
    (Impactfactor: 6,177)
    PDF Download (113 kB, Englisch, 5 Seiten) BibTeX-Ausgabe
  • Nicolas Wentzensen, Ulf-Dietrich Braumann, Jens Einenkel, Lars-Christian Horn, Magnus von Knebel Doeberitz, Markus Löffler, Jens-Peer Kuska
    (2007)
    Combined serial section-based 3D reconstruction of cervical carcinoma invasion using H&E/p16(INK4a)/CD3 alternate staining
    Cytometry Part A, 71A, 327-333
    (Impactfactor: 3,293)
    PDF Download (380 kB, Englisch, 7 Seiten) BibTeX-Ausgabe
  • Christoph Engel, Jochen Forberg, Elke Holinski-Feder, Constanze Pagenstecher, Jens Plaschke, Matthias Kloor, Christopher Poremba, Christian P. Pox, Josef Rüschoff, Gisela Keller, Wolfgang Dietmaier, Petra Rümmele, Nicolaus Friedrichs, Elisabeth Mangold, Reinhard Buettner, Hans K. Schackert, Peter Kienle, Susanne Stemmler, Gabriela Moeslein, Markus Loeffler, and the German HNPCC Consortium
    (2006)
    Novel strategy for optimal sequential application of clinical criteria, immunohistochemistry and microsatellite analysis in the diagnosis of hereditary nonpolyposis colorectal cancer
    International Journal of Cancer, 118, 115 - 122
    (Impactfactor: 4,416)
    PDF Download (233 kB, Englisch) BibTeX-Ausgabe
  • J. Galle, D. Sitting, I. Hanisch, M. Wobus, E. Wandel, M. Loeffler, G. Aust
    (2006)
    Incividal Cell-based Models of Tumor - Environment Interactions. Multiple Effects of CD97 on Tumor Invasion
    American Journal of Pathology, 169/5, 1802 - 1811
    (Impactfactor: 5,976)
    PDF Download (728 kB, Englisch, 10 Seiten) BibTeX-Ausgabe
  • B. Glass, M. Kloess, M. Bentz, G. Schlimok, W. E. Berdel, A. Feller, L. Truemper, M. Loeffler, M. Pfreundschuh, N. Schmitz
    (2006)
    Dose-escalated CHOP plus etoposide (MegaCHOEP) followed by repeated stem-cell transplantation for primary treatment of aggressive high-risk non-hodgkin's lymphoma
    Blood, 107, 3058-3064
    (Impactfactor: 10,131)
    PDF Download (186 kB, Englisch) BibTeX-Ausgabe
  • Timm Goecke, Karsten Schulmann, Christoph Engel, Elke Holinski-Feder, Constanze Pagenstecher, Hans K. Schackert, Matthias Kloor, Erdmute Kunstmann, Holger Vogelsang, Gisela Keller, Wolfgang Dietmaier, Elisabeth Mangold, Nicolaus Friedrichs, Peter Propping, Stefan Krüger, Johannes Gebert, Wolff Schmiegel, Josef Rueschoff, Markus Loeffler, Gabriela Moeslein, and the German HNPCC Consortium
    (2006)
    A genotype-phenotype comparison of 988 German MLH1 and MSH2 mutation carriers clinically affected with Lynch syndrome
    Journal of Clinical Oncology, 10, 4285 - 4292
    (Impactfactor: 11,81)
    PDF Download (343 kB, Englisch) BibTeX-Ausgabe
  • Michael Hummel, Stefan Bentink, Hilmar Berger, Wolfram Klapper, Swen Wessendorf, Thomas F.E. Barth, Heinz-Wolfram Bernd, Sergio B. Cogliatti, Judith Dierlamm, Alfred C. Feller, Martin-Leo Hansmann, Eugenia Haralambieva, Lana Harder, Dirk Hasenclever, Michael Kühn, Dido Lenze, Peter Lichter, Jose Ignacio Martin-Subero, Peter Möller, Hans-Konrad Müller-Hermelink, German Ott, Reza M. Parwaresch, Christiane Pott, Andreas Rosenwald, Maciej Rosolowski, Carsten Schwaenen, Benjamin Stürzenhofecker, Monika Szczepanowski, Heiko Trautmann, Hans-Heinrich Wacker, Rainer Spang, Markus Loeffler, Lorenz Trümper, Harald Stein, Reiner Siebert, for the Molecular Mechanisms in Malignant Lymphomas Network, Project of the Deutsche Krebshilfe
    (2006)
    A Biologic Definition of Burkitt's Lymphoma from Transcriptional and Genomic Profiling
    New England Journal of Medicine, 354/23, 2419-2430
    (Impactfactor: 44,016)
    PDF Download (1,4 MB, Englisch) BibTeX-Ausgabe
  • Michael Pfreundschuh, Lorenz Trümper, Anders Österborg, Ruth Pettengell, Marek Trneny, Kevin Imrie, David Ma, Devinder Gill, Jan Walewski, Pier-Luigi Zinzani, Rolf Stahel, Stein Kvaloy, Ofer Shpilberg, Ulrich Jaeger, Mads Hansen, Tuula Lehtinen, Armando López-Guillermo, Claudia Corrado, Adriana Scheliga, Noel Milpied, Myriam Medila, Michelle Rashford, Evelyn Kuhnt, Markus Loeffler, for the MabThera International Trial (MinT) Group
    (2006)
    CHOP-like chemotherapy plus rituyximab versus CHOP-like chemotherapy alone in young patients with good-prognosis diffuse large-B-cell lymphoma: a randomised controlled trial by the MabThera International Trial (MInT) Group
    Lancet Oncology, 7, 379-391
    (Impactfactor: 7,855)
    PDF Download (160 kB, Englisch) BibTeX-Ausgabe
  • Ingo Roeder, Matthias Horn, Ingmar Glauche, Andreas Hochhaus, Martin C. Mueller, Markus Loeffler
    (2006)
    Dynamic modeling of imatinib-treated chronic myeloid leukemia: functional insights and clinical implications
    Nature Medicine, 12/10, 1181 - 1184
    (Impactfactor: 28,878)
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  • N. Schmitz, M. Kloess, M. Reiser, W. E. Berdel, B. Metzner, B. Dorken, M. Kneba, L. Trümper, M. Loeffler, M. Pfreundschuh, B. Glass
    (2006)
    Four versus six courses of a dose-escalated cyclophosphamide doxorubicin, vincristine, and prednisone (CHOP) regimen plus etoposide (megaCHOEP) and autologous stem cell transplantation
    Cancer, 106 (1), 136-145
    (Impactfactor: 4,434)
    PDF Download (251 kB, Englisch) BibTeX-Ausgabe
  • Markus Scholz, Christoph Engel, Markus Loeffler
    (2006)
    Model-based design of chemotherapeutic regimens that account for heterogeneity in leucopoenia
    British Journal of Haematology, 132, 723-735
    (Impactfactor: 4,08)
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  • Anke Tönjes, Markus Scholz, Markus Loeffler, Michael Stumvoll
    (2006)
    Association of Pro12Ala Polymophism in Peroxisome Proliferator-Activated Receptor "gamma" With Pre-Diabetic Phenotypes
    Diabetes Care, 29, 2489-2497
    (Impactfactor: 7,844)
    PDF Download (1,3 MB, Englisch, 9 Seiten) BibTeX-Ausgabe
  • V. Ballova, J. U. Rüffer, H. Haverkamp, B. Pfistner, H. K. Müller-Hermelink, E. Dühmke, P. Worst, M. Wilhelmy, R. Naumann, M. Hentrich, H. T. Eich, A. Josting, M. Loeffler, V. Diehl, A. Engert
    (2005)
    A prospectively randomized trial carried out by the German Hodgkin Study Group (GHSG) for elderly patients with advanced Hodgkin's disease comparing BEACOPP baseline and COPP-ABVD (study HD9elderly)
    Annals of Oncology, 16 (1), 124 - 131
    (Impactfactor: 4,335)
    PDF Download (146 kB, Englisch) BibTeX-Ausgabe
  • Ulf-Dietrich Braumann, Jens-Peer Kuska, Jens Einenkel, Lars-Christian Horn, Markus Löffler, Michael Höckel
    (2005)
    Three-Dimensional Reconstruction and Quantification of Cervical Carcinoma Invasion Fronts From Histological Serial Sections
    IEEE Transactions on Medical Imaging, Vol. 24 / No. 10, 1286 - 1307
    (Impactfactor: 3,922)
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  • Jörg Galle, Markus Loeffler, Dirk Drasdo
    (2005)
    Modeling the Effect of Deregulated Proliferation and Apoptosis on the Growth Dynamics of Epithelial Cell Populations in Vitro
    Biophysical Journal, 88, 62-75
    (Impactfactor: 4,585)
    PDF Download (415 kB, Englisch) BibTeX-Ausgabe
  • U. Greiner, R. Mueller, E. Rahm, J. Ramsch, B. Heller, M. Loeffler
    (2005)
    AdaptFlow: protocol-based medical treatment using adaptive workflows
    Methods of Information in Medicine, 44 (1), 80-88
    (Impactfactor: 1,338)
    PDF Download (487 kB, Englisch) BibTeX-Ausgabe
  • E. Mangold, C. Pagenstecher, W. Friedl, M. Mathiak, R. Buettner, C. Engel, M. Loeffler, E. Holinski-Feder, Y. Müller-Koch, G. Keller, H. K. Schackert, S. Krüger, T. Goecke, G. Moeslein, M. Kloor, J. Gebert, E. Kunstmann, K. Schulmann, J. Rüschoff, P. Propping, and The German HNPCC Consortium
    (2005)
    Spectrum and frequencies of mutations in MSH2 and MLH1 identified in 1721 German families suspected of Hereditary Nonpolyposis Colorectal Cancer
    International Journal of Cancer, 116, 692 - 702
    (Impactfactor: 4,416)
    PDF Download (125 kB, Englisch) BibTeX-Ausgabe
  • P. Mauch, A. Ng, B. Aleman, P. Carde, L. Constine, V. Diehl, K. Dinshaw, M. Gospodarowicz, S. Hancock, D. Hodgson, R. Hoppe, R. Liang, M. Loeffler, L. Specht, L. B. Travis, A. Wirth, J. Yahalom
    (2005)
    Report from the Rockefeller Foundation Sponsored International Workshop on reducing mortality and improving quality of life in long-term survivors of Hodgkin's disease: Bellagio 2003
    European Journal of Haematology, Suppl. 66 Vol. 75 (66), 68-76
    (Impactfactor: 1,729)
    PDF Download (566 kB, Englisch) BibTeX-Ausgabe
  • I. Roeder, M. Kamminga, K. Braesel, B. Dontje, G. de Haan, M. Loeffler
    (2005)
    Competitive clonal hematopoiesis in mouse chimeras explained by a stochastic model of stem cell organization
    Blood, 15 / 2, 609 - 616
    (Impactfactor: 9,782)
    PDF Download (284 kB, Englisch, 8 Seiten) BibTeX-Ausgabe
  • Rita Katharina Schmutzler, Markus Löffler, Jörgen Windeler, Stefanie Thomas, Johannes Bruns, Thomas Rath
    (2005)
    Von der Forschung zur Regelversorgung (Familiärer Brust- und Eierstockkrebs)
    Deutsches Ärzteblatt, Jg.102/Heft 50, 3486-3488
    PDF Download (910 kB) BibTeX-Ausgabe
  • M. Scholz, C. Engel, M. Loeffler
    (2005)
    Modelling Human Granulopoiesis under Polychemotherapy with G-CSF Support
    Journal of Mathematical Biology, 50(4), 397-439
    (Impactfactor: 1,412)
    PDF Download (769 kB, Englisch, 43 Seiten) BibTeX-Ausgabe
  • Leszek Wojnowski, Bettina Kulle, Markus Schirmer, Gregor Schlüter, Albrecht Schmidt, Albert Rosenberger, Stefan Vonhof, Heike Bickeböller, Mohammad Reza Toliat, Eun-Kyung Suk, Mladen Tzvetkov, Anke Kruger, Silvia Seifert, Marita Kloess, Heidi Hahn, Markus Loeffler, Peter Nürnberg, Michael Pfreundschuh, Lorenz Trümper, Jürgen Brockmöller, Gerd Hasenfuss
    (2005)
    NAD(P)H oxidase and MRP genetic polymorphisms are associated with doxorubicin-induced cardiotoxicity
    CIRCULATION, 112 (24), 3754-3762
    (Impactfactor: 1,758)
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  • H. Binder, T. Kirsten, I. L. Hofacker, P. F. Stadler, M. Loeffler
    (2004)
    Interactions in Oligonucleotide Hybrid Duplexes on Microarrays
    J. Phys. Chem. B, 108 (46), 18015 - 18025
    (Impactfactor: 3,679)
    PDF Download (491 kB, Englisch, 11 Seiten) BibTeX-Ausgabe
  • H. Binder, T. Kirsten, M. Loeffler, P.F. Stadler
    (2004)
    Sensitivity of Microarray Oligonucleotide Probes: Variability and the Effect of Base Composition
    J. Phys. Chem. B, 108 (46), 18003-18014
    (Impactfactor: 3,679)
    PDF Download (919 kB, Englisch, 12 Seiten) BibTeX-Ausgabe
  • O. Brosteanu, D. Hasenclever, M. Loeffler, V. Diehl, Group GH
    (2004)
    Low acute hematological toxicity during chemotherapy predicts reduced disease control in advanced Hodgkin's disease
    Annals of Hematology, 83 (3), 176 - 182
    (Impactfactor: 1,241)
    PDF Download (277 kB, Englisch, 7 Seiten) BibTeX-Ausgabe
  • C. Engel, M. Scholz, M. Löffler
    (2004)
    A computational model of human granulopoiesis to simulate the hematotoxic effects of multicycle polychemotherapy
    Blood, Volume 104, Number 8, 2323-2331
    PDF Download (343 kB, Englisch, 9 Seiten) BibTeX-Ausgabe
  • U. Greiner, J. Ramsch, B. Heller, M. Löffler, R. Müller, E. Rahm
    (2004)
    Adaptive Guideline-based Treatment Workflows with AdaptFlow
    Stud. Health Technol. Inform., 101, 113-117
    PDF Download (43 kB, Englisch, 5 Seiten) BibTeX-Ausgabe
  • B. Heller, H. Herre, K. Lippoldt, M. Loeffler
    (2004)
    Standardized Terminology for Clinical Trial Protocols Based on Ontological Top-Level Categories
    Studies in Health Technology and Informatics, 101, 46 - 60
    PDF Download (102 kB, Englisch, 15 Seiten) BibTeX-Ausgabe
  • M. Löffler, I. Roeder
    (2004)
    Conceptual models to understand tissue stem cell organization
    Current Opinion in Hematology, 11, 81-87
    (Impactfactor: 2,7)
    PDF Download (870 kB, Englisch, 7 Seiten) BibTeX-Ausgabe
  • M. Pfreundschuh, L. Trümper, M. Kloess, R. Schmits, A.C. Feller, C. Rudolph, M. Reiser, D. Hossfeld, B. Metzner, D. Hasenclever, N. Schmitz, B. Glass, C. Rübe, M. Loeffler
    (2004)
    Two-weekly or 3-weekly CHOP chemotherapy with or without etoposide for the treatment of young patients with good-prognosis (normal LDH) aggressive lymphomas: results of the NHL-B1 trial of the DSHNHL
    Blood, Volume 104, Number 3, 626 - 633
    (Impactfactor: 10,12)
    PDF Download (106 kB, Englisch, 8 Seiten) BibTeX-Ausgabe
  • M. Pfreundschuh, L. Trümper, M. Kloess, R. Schmits, A.C. Feller, C. Rübe, C. Rudolph, M. Reiser, D. K. Hossfeld, H. Eimermacher, D. Hasenclever, N. Schmitz, M. Löffler
    (2004)
    Two-weekly or 3-weekly CHOP chemotherapy with or without etoposide for the treatment of elderly patients with aggressive lymphomas: results of the NHL-B2 trial of the DSHNHL
    Blood, Volume 104, Number 3, 634 - 641
    (Impactfactor: 10,12)
    PDF Download (81 kB, Englisch, 8 Seiten) BibTeX-Ausgabe
  • J. Plaschke, C. Engel, S. Krüger, E. Holinksi-Feder, C. Pagenstecher, E. Mangold, G. Moeslein, K. Schulmann, J. Gebert, M. von Knebel Doeberitz, J. Rüschoff, M. Loeffler, H. K. Schackert
    (2004)
    Lower Incidence of Colorectal Cancer and Later Age of Disease Onset in 27 Families with Pathogenic MSH6 Germline Mutations Compared with Families with MLH1 or MSH2 Mutations: The German Hereditary Nonpolyposis Colorectal Cancer Consortium
    Journal of Clinical Oncology, Vol. 22 Nr. 22, 4486 - 4494
    (Impactfactor: 10,864)
    PDF Download (167 kB, Englisch, 9 Seiten) BibTeX-Ausgabe
  • M. Sieber, H. Tesch, B. Pfistner, U. Rueffer, U. Paulus, R. Munker, R. Hermann, G. Doelken, P. Koch, J. Oertel, S. Roller, P. Worst, H. Bischof, A. Glunz, R. Greil, K. von Kalle, K. P. Schalk, D. Hasenclever, O. Brosteanu, E. Duehmke, A. Georgii, A. Engert, M. Loeffler, V. Diehl
    (2004)
    Treatment of advance Hodgkin's disease with COPP/ABV/IMEP versus COPP/ABVD and consolidating radiotherapy: final results of the German Hodgkin's Lymphoma Study Group HD6 trial
    Annals of Oncology, 15 (2), 276-282
    (Impactfactor: 3,605)
    PDF Download (127 kB, Englisch, 7 Seiten) BibTeX-Ausgabe
  • V. Diehl, J. Franklin, M. Pfreundschuh, B. Lathan, U. Paulus, D. Hasenclever, H. Tesch, R. Hermann, B. Dorken, H.-K. Müller-Hermelink, E. Dühmke, M. Loeffler
    (2003)
    Standard and increased-dose BEACOPP chemotherapy compared with COPP-ABVD for advanced Hodgkin's disease.
    New England Journal of Medicine, 348(24), 2386-2395
    (Impactfactor: 31,736)
    PDF Download (114 kB, Englisch, 10 Seiten) BibTeX-Ausgabe
  • A. Engert, P. Schiller, A. Josting, R. Hermann, P. Koch, M. Sieber, F. Boissevain, M. De Wit, J. Mezger, E. Dühmke, N. Willich, R.P. Müller, B.F. Schmidt, H. Renner, H.-K. Müller-Hermelink, B. Pfistner, J. Wolf, D. Hasenclever, M. Löffler, V. Diehl
    (2003)
    Involved-Field Radiotherapy Is Equally Effective and Less Toxic Compared With Extended-Field Radiotherapy After Four Cycles of Chemotherapy in Patients With Early-Stage Unfavorable Hodgkin's Lymphoma: Results of the HD8 Trial of the GHSG
    Journal of Clinical Oncology, 21(19), 3601-3608
    (Impactfactor: 9,868)
    PDF Download (1,2 MB, Englisch, 10 Seiten) BibTeX-Ausgabe
  • B. Pfistner, C. Mehl, M. Klöss, M. Löffler, A. Herrmann-Frank, V. Diehl
    (2003)
    Qualitätsstandards und ihre Sicherung für Studienzentralen im Kompetenznetz Maligne Lymphome.
    Klinische Pädiatrie, 215(6), 341-344
    (Impactfactor: 0,457)
    PDF Download (106 kB, 4 Seiten) BibTeX-Ausgabe
  • I. Roeder, M. Loeffler, P.J. Quesenberry, G.A. Colvin, J.F. Lambert
    (2003)
    Quantitative tissue stem cell modeling.
    Blood, 102(3), 1143-1144
    (Impactfactor: 9,631)
    PDF Download (85 kB, Englisch, 3 Seiten) BibTeX-Ausgabe
  • A. Treide, B. Hentschel, A. Makuch, M. Löffler
    (2003)
    Die Ermittlung des Kariesrisikos unter den Bedingungen des Caries decline in Deutschland.
    Deutsche Zahnärztliche Zeitschrift, 58(1), 26-31
    PDF Download (859 kB, 7 Seiten) BibTeX-Ausgabe
  • A. Wunderlich, M. Kloess, M. Reiser, C. Rudolph, L. Trümper, S. Bittner, H. Schmalenberg, R. Schmits, M. Pfreundschuh, M. Loeffler
    (2003)
    Practicability and acute haematological toxicity of 2- and 3-weekly CHOP and CHOEP chemotherapy for aggressive non-Hodgkin's lymphoma: results from the NHL-B trial of the German High-Grade Non-Hodgkin's Lymphoma Study Group (DSHNHL).
    Annals of Oncology, 14(6), 881-893
    (Impactfactor: 3,114)
    PDF Download (1,2 MB, Englisch, 13 Seiten) BibTeX-Ausgabe
  • D. Barthel, F. Meineke, C.S. Potten, M. Loeffler
    (2002)
    A continuum model to analyse spatial cell fluxes from positional labelling data applied to cell migration in oral mucosa.
    Cell Proliferation, 35(S1), 48-59
    (Impactfactor: 1,617)
    PDF Download (266 kB, Englisch, 12 Seiten) BibTeX-Ausgabe
  • M. Loeffler, I. Roeder
    (2002)
    Tissue Stem Cells: Definition, Plasticity, Heterogeneity, Self Organization and Models - A Conceptual Approach.
    Cells Tissues Organs, 171(1), 8-26
    (Impactfactor: 1,071)
    PDF Download (354 kB, Englisch, 19 Seiten) BibTeX-Ausgabe
  • M. Löffler
    (2002)
    Modelling the effects of ccontinuous irradiation on murine haematopoiesis.
    British Journal of Radiology, S26, 188-197
    (Impactfactor: 0,959)
    PDF Download (477 kB, Englisch, 10 Seiten) BibTeX-Ausgabe
  • C.S. Potten, D. Booth, N.J. Cragg, G.L. Tudor, J.A. O‘Shea, C. Booth, F. Meineke, D. Barthel, M. Loeffler
    (2002)
    Cell kinetic studies in the murine ventral tongue epithelium: mucositis induced by radiation and its protection by pretreatment with keratinocyte growth factor (KGF).
    Cell Proliferation, 35(S1), 32-47
    (Impactfactor: 1,617)
    PDF Download (751 kB, Englisch, 16 Seiten) BibTeX-Ausgabe
  • C.S. Potten, D. Booth, N.J. Cragg, G.L. Tudor, J.A. O‘Shea, D. Appleton, D. Barthel, T. Gerike, F. Meineke, M. Loeffler, C. Booth
    (2002)
    Cell kinetic studies in the murine ventral tongue epithelium: thymidine metabolism studies and circadian rhythm determination.
    Cell Proliferation, 35(S1), 1-15
    (Impactfactor: 1,617)
    PDF Download (319 kB, Englisch, 15 Seiten) BibTeX-Ausgabe
  • I. Roeder, M. Loeffler
    (2002)
    A novel dynamic model of hematopoietic stem cell organization based on the concept of within-tissue plasticity.
    Experimental Hematology, 30(8), 853-861
    (Impactfactor: 3,328)
    PDF Download (471 kB, Englisch, 9 Seiten) BibTeX-Ausgabe
  • M. Sieber, H. Tesch, B. Pfistner, U. Rueffer, B. Lathan, O. Brosteanu, U. Paulus, T. Koch, M. Pfreundschuh, M. Loeffler, A. Engert, A. Josting, J. Wolf, D. Hasenclever, J. Franklin, E. Dühmke, A. Georgii, K.P. Schalk, H. Kirchner, G. Doelken, R. Munker, P. Koch, R. Hermann, R. Greil, A.P. Anselmo, V. Diehl
    (2002)
    Rapidly Alternating COPP/ABV/IMEP Is Not Superior to Conventional Alternating COPP/ABVD in Combination With Extended-Field Radiotherapy in Intermediate-Stage Hodgkin's Lymphoma: Final Results of the German Hodgkin's Lymphoma Study Group Trial HD5.
    Journal of Clinical Oncology, 20(2), 476-484
    (Impactfactor: 8,53)
    PDF Download (195 kB, Englisch, 9 Seiten) BibTeX-Ausgabe
  • D. Drasdo, M. Loeffler
    (2001)
    Individual-based models on growth and folding in one-layered tissues: Intestinal Crypts and early development.
    Nonlinear Analysis, 47, 245-256
    (Impactfactor: 0,458)
    PDF Download (590 kB, Englisch, 12 Seiten) BibTeX-Ausgabe
  • E. Dühmke, J. Franklin, M. Pfreundschuh, S. Sehlen, N. Willich, U. Rühl, R.P. Müller, P. Lukas, A. Atzinger, U. Paulus, B. Lathan, U. Rueffer, M. Sieber, J. Wolf, A. Engert, A. Georgii, S. Staar, R. Hermann, M. Beykirch, H. Kirchner, A. Emminger, R. Greil, E. Fritsch, P. Koch, A. Drochtert, O. Brosteanu, D. Hasenclever, M. Loeffler, V. Diehl
    (2001)
    Low-dose radiation is sufficient for the noninvolved extended-field treatment in favorable early-stage Hodgkin's disease: long-term results of a randomized trial of radiotherapy alone.
    Journal of Clinical Oncology, 19(11), 2905-2914
    (Impactfactor: 8,773)
    PDF Download (96 kB, Englisch, 10 Seiten) BibTeX-Ausgabe
  • D. Hasenclever, O. Brosteanu, T. Gerike, M. Loeffler
    (2001)
    Modelling of chemotherapy: The effective dose approach.
    Annals of Hematology, 80(S3), B89-94
    (Impactfactor: 1,448)
    PDF Download (58 kB, Englisch, 6 Seiten) BibTeX-Ausgabe
  • D. Hasenclever, M. Loeffler
    (2001)
    Five theses concerning the clinical consequences of pathology and prognostic factors.
    Annals of Hematology, 80(S3), B58-60
    (Impactfactor: 1,448)
    PDF Download (22 kB, Englisch, 3 Seiten) BibTeX-Ausgabe
  • S. Kaltenhäuser, U. Wagner, E. Schuster, R. Wassmuth, S. Arnold, W. Seidel, M. Troltzsch, M. Loeffler, H. Häntzschel
    (2001)
    Immunogenetic markers and seropositivity predict radiological progression in early rheumatoid arthritis independent of disease activity.
    J. Rheumatol., 28(4), 735-744
    (Impactfactor: 2,91)
    PDF Download (5,9 MB, Englisch, 11 Seiten) BibTeX-Ausgabe
  • M. Loeffler, M. Shipp, H. Stein
    (2001)
    2. Report on the Workshop: ?Clinical Consequences of Pathology and Prognostic Factors in Aggressive NHL".
    Annals of Hematology, 80(S3), B8-12
    (Impactfactor: 1,448)
    PDF Download (33 kB, Englisch, 7 Seiten) BibTeX-Ausgabe
  • F. Meineke, C.S. Potten, M. Loeffler
    (2001)
    Cell migration and organization in the intestinal crypt using a lattice-free model.
    Cell Proliferation, 34(4), 253-266
    (Impactfactor: 0,955)
    PDF Download (834 kB, Englisch, 14 Seiten) BibTeX-Ausgabe
  • M. Pfreundschuh, D. Hasenclever, M. Loeffler, G. Ehninger, N. Schmitz, H. Kirchner, P. Koch, B. Lathan, U. Rueffer, M. Sextro, J. Franklin, H. Tesch, V. Diehl
    (2001)
    Dose escalation of cytotoxic drugs using haematopoietic growth factors: a randomized trial to determine the magnitude of increase provided by GM-CSF.
    Annals of Oncology, 12(4), 471-477
    (Impactfactor: 3,249)
    PDF Download (120 kB, Englisch, 7 Seiten) BibTeX-Ausgabe
  • C. Rübe, T.P. Nguyen, M. Klöss, M. Loeffler, L. Trümper, M. Pfreundschuh
    (2001)
    Consolidation radiotherapy to bulky disease in aggressive NHL. First results of the NHL B-94 trial of the DSHNHL.
    Annals of Hematology, 80(S3), B84-85
    (Impactfactor: 1,448)
    BibTeX-Ausgabe
  • D. Barthel, B. Matthé, C.S. Potten, G. Owen, M. Loeffler
    (2000)
    Proliferation in murine epidermis after minor mechanical stimulation - Part 2: Alterations in keranocyte cell cycle fluxes.
    Cell Proliferation, 33, 247-259
    (Impactfactor: 0,913)
    PDF Download (146 kB, Englisch, 13 Seiten) BibTeX-Ausgabe
  • C. Engel, M. Loeffler, S. Schmitz, H. Tesch, V. Diehl
    (2000)
    Acute hematologic toxicity and practicability of dose-intensified BEACOPP chemotherapy for advanced stage Hodgkin's disease.
    Annals of Oncology, 11, 1105-1114
    (Impactfactor: 3,195)
    PDF Download (375 kB, Englisch, 10 Seiten) BibTeX-Ausgabe
  • M. Löffler, D. Hasenclever, O. Brosteanu, U. Paulus, V. Diehl
    (2000)
    Modell- und evidenzbasierte Planung klinischer Studien beim Hodgkin Lymphom.
    Der Onkologe, 6(12), 1197-1201
    (Impactfactor: 0,382)
    PDF Download (112 kB, 5 Seiten) BibTeX-Ausgabe
  • L. Mantovani, G. Lentini, B. Hentschel, P.D. Wickramanayake, M. Loeffler, V. Diehl, H. Tesch
    (2000)
    Treatment of anaemia in myelodysplastic syndromes with prolonged administration of recombinant human granulocyte colony-stimulating factor and erythropoietin.
    British Journal of Haematology, 109, 367-375
    (Impactfactor: 3,204)
    PDF Download (198 kB, Englisch, 9 Seiten) BibTeX-Ausgabe
  • B. Pfistner, U. Paulus, M. Löffler, J.-P. Glossmann, J. Wolf, V. Diehl
    (2000)
    Qualitätsmanagement in Therapieoptimierungsstudien der Deutschen Hodgkin Lymphom Studiengruppe (DHSG).
    Der Onkologe, 6(12), 1202-1204
    (Impactfactor: 0,382)
    PDF Download (60 kB, 3 Seiten) BibTeX-Ausgabe
  • C.S. Potten, D. Barthel, Y.Q. Li, R. Ohlrich, B. Matthé, M. Loeffler
    (2000)
    Proliferation in murine epidermis after minor mechanical stimulation - Part 1: Sustained increase in keranocyte production and migration.
    Cell Proliferation, 33, 231-246
    (Impactfactor: 0,913)
    PDF Download (253 kB, Englisch, 16 Seiten) BibTeX-Ausgabe
  • C. Engel, M. Loeffler, H. Franke, N. Schmitz
    (1999)
    Endogenous thrombopoietin serum levels during multicycle chemotherapy.
    British Journal of Haematology, 105, 832-838
    (Impactfactor: 3,209)
    PDF Download (431 kB, Englisch) BibTeX-Ausgabe
  • M. Shipp, M.D. Abeloff, K.H. Antman, G. Carroll, A. Hagenbeek, M. Loeffler, E. Montserrat, J.A. Radford, G. Salles, N. Schmitz, M. Symann, J.O. Armitage, B. Coiffier, T. Philip
    (1999)
    International Consensus Conference on high-dose therapy with hematopoietic stem-cell transplantation in aggressive non-Hodgkin's lymphomas: report of the jury.
    Annals of Oncology, 10(1), 13-19
    (Impactfactor: 2,876)
    PDF Download (782 kB, Englisch) BibTeX-Ausgabe
  • M. Shipp, M.D. Abeloff, K.H. Antman, G. Carroll, A. Hagenbeek, M. Loeffler, E. Montserrat, J.A. Radford, G. Salles, N. Schmitz, M. Symann, J.O. Armitage, T. Philip, B. Coiffier
    (1999)
    International Consensus Conference on High-Dose Therapy with Hematopoietic Stem Cell Transplantation in Aggressive Non-Hodgkin's Lymphomas: report of the jury.
    Journal of Clinical Oncology, 17(1), 423-429
    (Impactfactor: 8,228)
    BibTeX-Ausgabe
  • O. Brosteanu, M. Loeffler
    (1998)
    Methoden kontrollierter klinischer Studien.
    Internist, 39(9), 909-916
    (Impactfactor: 0,286)
    PDF Download (1,8 MB) BibTeX-Ausgabe
  • V. Diehl, J. Franklin, D. Hasenclever, H. Tesch, M. Pfreundschuh, B. Lathan, U. Paulus, M. Sieber, U. Rueffer, M. Sextro, A. Engert, J. Wolf, R. Hermann, L. Holmer, U. Stappert-Jahn, E. Winnerlein-Trump, G. Wulf, S. Krause, A. Glunz, K. von Kalle, H. Bischoff, Ch. Haedicke, E. Dühmke, A. Georgii, M. Loeffler
    (1998)
    BEACOPP, a New Dose-Escalated and Accelerated Regimen, Is at Least as Effective as COPP/ABVD in Patients With Advanced-Stage Hodgkin's Lymphoma: Interim Report From a Trial of the GHSG.
    Journal of Clinical Oncology, 16(12), 3810-3821
    (Impactfactor: 7,878)
    PDF Download (1,3 MB, Englisch) BibTeX-Ausgabe
  • V. Diehl, J. Franklin, D. Hasenclever, H. Tesch, M. Pfreundschuh, B. Lathan, U. Paulus, M. Sieber, U. Rueffer, M. Sextro, A. Engert, J. Wolf, R. Hermann, L. Holmer, U. Stappert-Jahn, E. Winnerlein-Trump, G. Wulf, S. Krause, A. Glunz, K. von Kalle, H. Bischoff, Ch. Haedicke, E. Dühmke, A. Georgii, M. Loeffler
    (1998)
    BEACOPP: A new regimen for advanced Hodgkin's disease.
    Annals of Oncology, 9, S67-S71
    (Impactfactor: 2,548)
    PDF Download (536 kB, Englisch) BibTeX-Ausgabe
  • V. Diehl, J. Wolf, R. Walshe, H. Tesch, M. Löffler
    (1998)
    Die Therapie des Morbus Hodgkin - Optimierung über vier Studiengenerationen.
    Internist, 39(9), 917-926
    (Impactfactor: 0,286)
    PDF Download (2,2 MB) BibTeX-Ausgabe
  • T. Gerike, U. Paulus, C.S. Potten, M. Loeffler
    (1998)
    A dynamic model of proliferation and differentiation in the intestinal crypt based on a hypothetical intraepithelial growth factor.
    Cell Proliferation, 31, 93-110
    (Impactfactor: 1,396)
    PDF Download (1,5 MB, Englisch) BibTeX-Ausgabe
  • M. Loeffler
    (1998)
    Biometrische Grundlagen der Medizin.
    Medizinische Klinik, 93, 571-576
    (Impactfactor: 0,386)
    PDF Download (912 kB) BibTeX-Ausgabe
  • M. Loeffler, O. Brosteanu, D. Hasenclever, M. Sextro, D. Assouline, A.A. Bartolucci, P.A. Cassileth, D. Crowther, V. Diehl, R.I. Fisher, R.T. Hoppe, P. Jacobs, J.L. Pater, S. Pavlovsky, E. Thompson, P. Wiernik
    (1998)
    Meta-Analysis of chemotherapy versus combined modality treatment trials in Hodgkin's disease.
    Journal of Clinical Oncology, 16(3), 818-829
    (Impactfactor: 7,878)
    PDF Download (1,1 MB, Englisch) BibTeX-Ausgabe
  • M. Loeffler, D. Hasenclever, V. Diehl
    (1998)
    Model Based development of the BEACOPP regimen for advanced stage Hodgkin's disease.
    Annals of Oncology, 9, S73-S78
    (Impactfactor: 2,548)
    PDF Download (573 kB, Englisch) BibTeX-Ausgabe
  • I. Roeder, G. de Haan, C. Engel, W. Nijhof, B. Dontje, M. Loeffler
    (1998)
    Interactions of erythropoietin (EPO), granulocyte-colony stimulating factor, stem cell factor and interleukin-11 on murine hemopoiesis during simultaneous administration.
    Blood, 91(9), 3222-3229
    (Impactfactor: 9,507)
    PDF Download (1,8 MB, Englisch) BibTeX-Ausgabe
  • I. Roeder, M. Loeffler
    (1998)
    Modeling the clonal dynamics of primitive hemopoiesis in vivo.
    Experimental Hematology, 26(8), 731
    BibTeX-Ausgabe
  • H. Tesch, V. Diehl, B. Lathan, D. Hasenclever, M. Sieber, U. Rueffer, A. Engert, J. Franklin, M. Pfreundschuh, K.P. Schalk, G. Schwieder, G. Wulf, G. Doelken, P. Worst, P. Koch, N. Schmitz, U. Bruntsch, C. Tirier, U. Müller, M. Loeffler
    (1998)
    Moderate Dose Escalation for Advanced Stage Hodgkin's Disease Using the Bleomycin, Etoposide, Adriamycin, Cyclophosphamide, Vincristine, Procarbazine and Prednisone Scheme and Adjuvant Radiotherapy: A Study of the German Hodgkin's Lymphoma Study Group.
    Blood, 92(12), 4560-4567
    (Impactfactor: 9,507)
    PDF Download (785 kB, Englisch) BibTeX-Ausgabe
  • A. Tsodikov, D. Hasenclever, M. Loeffler
    (1998)
    Regression with bounted outcome score: Evaluation of power by bootstrap and simulation in a chronic myelogenous leukemia clinical trial.
    Statistics in Medicine, 17, 1909-1922
    (Impactfactor: 1,003)
    PDF Download (1006 kB, Englisch) BibTeX-Ausgabe
  • A. Tsodikov, M. Löffler, A.Yu. Yakovlev
    (1998)
    A cure model with time-changing risk factor: An application to the analysis of secondary leukemia. A report from the International Database on Hodgkin's Diseaese.
    Statistics in Medicine, 17, 27-40
    (Impactfactor: 1,003)
    PDF Download (997 kB, Englisch) BibTeX-Ausgabe
  • V. Diehl, M. Sieber, U. Rueffer, B. Lathan, D. Hasenclever, M. Pfreundschuh, M. Loeffler, D. Lieberz, P. Koch, M. Adler, H. Tesch
    (1997)
    BEACOPP: An intensified chemotherapy regimen in advanced Hodgkin's disease.
    Annals of Oncology, 8, 143-148
    (Impactfactor: 2,736)
    BibTeX-Ausgabe
  • M. Loeffler, T. Bratke, U. Paulus, Y.Q. Li, C.S. Potten
    (1997)
    Clonality and Life Cycles of Intestinal Crypts Explained by State Dependent Stochastic Model of Epithelial Stem Cell Organisation.
    Journal of Theoretical Biology, 186, 41-54
    (Impactfactor: 1,11)
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  • M. Loeffler, V. Diehl, M. Pfreundschuh, U. Rühl, D. Hasenclever, et al.
    (1997)
    Dose-Response Relationship of Complementary Radiotherapy Following Four Cycles of Combination Chemotherapy in Intermediate-Stage Hodgkin's Disease.
    Journal of Clinical Oncology, 15(6), 2275-2287
    (Impactfactor: 7,881)
    PDF Download (1,2 MB, Englisch) BibTeX-Ausgabe
  • G. de Haan, B. Dontje, C. Engel, M. Löffler, W. Nijhof
    (1996)
    Prophylactic pretreatment with hematopoietic growth factors induces expansions of primitive cell compartements and results in protection against 5-fluorouracil-induced toxicity.
    Blood, 87(11), 4581-4588
    (Impactfactor: 8,569)
    PDF Download (950 kB, Englisch) BibTeX-Ausgabe
  • E. Dühmke, V. Diehl, M. Löffler, R.P. Müller, U. Rühl, N. Willich, A. Georgii, S. Roth, D. Matthaei, S. Sehlen, O. Brosteanu, D. Hasenclever, R. Wilkowski, K. Becker
    (1996)
    Randomized trial with early-stage hodgkin's disease testing 30 Gy vs. 40 Gy extended field radiotherapy alone.
    Int. J. of Radiat. Oncol. Biol. Phys., 36, 305-310
    (Impactfactor: 2,484)
    PDF Download (617 kB, Englisch) BibTeX-Ausgabe
  • D. Hasenclever, M. Löffler, V. Diehl
    (1996)
    Rationale for dose escalation of first line conventional chemotherapy in advanced Hodgkin's disease.
    Annals of Oncology, 7(Suppl.4), S95-S98
    (Impactfactor: 2,736)
    PDF Download (445 kB, Englisch) BibTeX-Ausgabe
  • R. Hofestädt, M. Löffler, T. Lengauer
    (1996)
    Informatik in den Biowissenschaften.
    it+ti - Informationstechnik und Technische Informatik, 38, 5-7
    PDF Download (8,7 MB) BibTeX-Ausgabe
  • S. Schmitz, H. Franke, M. Loeffler, H.E. Wichmann, V. Diehl
    (1996)
    Model analysis of the contrasting effects of GM-CSF and G-CSF treatment on peripheral blood neutrophils observed in three patients with childhood-onset cyclic neutropenia.
    British Journal of Haematology, 95(4), 616-625
    (Impactfactor: 2,568)
    PDF Download (714 kB, Englisch) BibTeX-Ausgabe
  • G. de Haan, B. Dontje, W. Nijhof, M. Löffler
    (1995)
    Effects of continuous stem cell factor administration on normal and erythropoietin-stimulated murine hemopoiesis: experimental results and model analysis.
    Stem Cells (Dayt), 13(1), 65-76
    (Impactfactor: 0,838)
    PDF Download (1,3 MB, Englisch) BibTeX-Ausgabe
  • G. de Haan, B. Dontje, C. Engel, M. Löffler, W. Nijhof
    (1995)
    In vivo effects of interleukin-11 and stem cell factor in combination with erythropoietin in the regulation of erythropoiesis.
    British Journal of Haematology, 90(4), 783-790
    (Impactfactor: 2,568)
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  • G. de Haan, B. Dontje, C. Engel, W. Nijhof, M. Löffler
    (1995)
    The kinetics of murine hematopoietic stem cells in vivo in in response to prolonged increased mature blood cell production induced by granulocyte colony-stimulating factor.
    Blood, 86(8), 2986-2992
    (Impactfactor: 8,569)
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  • G. de Haan, C. Engel, B. Dontje, M. Löffler, W. Nijhof
    (1995)
    Hemotoxicity by prolonged etoposide administration to mice can be prevented by simultaneous growth factor therapy.
    Cancer Research, 55(2), 324-329
    (Impactfactor: 6,822)
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  • V. Diehl, M. Löffler, M. Pfreundschuh, U. Rühl, D. Hasenclever, et al.
    (1995)
    Further chemotherapy versus low-dose involved-field radiotherapy as consolidation of complete remission after six cycles of alternating chemotherapy in patients with advanced Hodgkin's Disease.
    Annals of Oncology, 6, 901-910
    (Impactfactor: 2,256)
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  • P. Dreger, M. Klöss, B. Petersen, T. Haferlach, H. Löffler, M. Löffler, N. Schmitz
    (1995)
    Autologous Progenitor Cell Transplantation: Prior Exposure to Stem Cell-Toxic Drugs Determines Yield and Engraftment of Peripheral Blood Progenitor Cell But Not of Bone Marrow Grafts.
    Blood, 86, 3970-3978
    (Impactfactor: 8,569)
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  • R. Hofestädt, M. Löffler, K. Möller
    (1995)
    Modellierung des Immunsystems.
    Informatik Bericht Universität Bonn, 88
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  • A. Lohri, S. Leyvraz, T. Cerny, U. Hess, H.P. Honegger, R. Greiner, M. Castiglione, R. Hermann, M. Löffler, D. Hasenclever, V. Diehl
    (1995)
    Participation in multicenter studies as quality control in the therapy of Hodgkin disease: an interim report.
    Schweizer Medizinische Wochenschrift, 125(6), 217-224
    (Impactfactor: 0,31)
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  • G. de Haan, C. Engel, B. Dontje, W. Nijhof, M. Löffler
    (1994)
    Mutual inhibition of murine erythropiesis and granulopoiesis during combined erythropoietin, granulocyte colony-stimulating factor, and stem cell factor administration: in vivo interactions and dose-response surfaces.
    Blood, 84(12), 4157-4163
    (Impactfactor: 8,279)
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  • R. Fuchs, M. Löffler, M. Pfreundschuh, G. Doelken, H. Gerhartz, U. Hagen-Aukamp, E. Hiller, S. Petsch, K.H. Pfluger, U. Rühl
    (1994)
    Prognosis of high dose chemotherapy/autologous bone marrow transplantation candidates not receiving this treatment after failure of primary therapy of Hodgkin's disease.
    Leukemia and Lymphoma, 14(1-2), 79-89
    (Impactfactor: 0,568)
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  • Y.Q. Li, S.A. Roberts, U. Paulus, M. Löffler, C.S. Potten
    (1994)
    The crypt cycle in mouse small intestinal epithelium.
    Journal of Cell Science, 107(12), 3271-3279
    (Impactfactor: 4,336)
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  • M. Pfreundschuh, U. Rueffer, B. Lathan, N. Schmitz, O. Brosteanu, D. Hasenclever, P. Haas, H. Kirchner, P. Koch, R. Kuse, M. Löffler, V. Diehl
    (1994)
    DexaBEAM in Patients with Hodgkin's Disease Refractory to multi-drug Chemotherapy regimens: A trial of the German Hodgkin's Disease Study Group.
    Journal of Clinical Oncology, 12, 580-586
    (Impactfactor: 7,507)
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  • S. Schmitz, H. Franke, M. Löffler, H.E. Wichmann, V. Diehl
    (1994)
    Reduced variance of bone-marrow transit time of granulopoiesis - a possible pathomechanism of human cyclic neutropenia.
    Cell Proliferation, 27, 655-667
    (Impactfactor: 1,849)
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